松果体血管加压素：由促黑素细胞激素释放抑制因子释放至猫的脑脊液中。

Pineal vasotocin: release into cat cerebrospinal fluid by melanocyte-stimulating hormone release-inhibiting factor.

作者信息

Pavel S, Goldstein R, Gheorghiu C, Calb M

出版信息

Science. 1977 Jul 8;197(4299):178-9. doi: 10.1126/science.17916.

Abstract

The intracarotid injection of both synthetic melanocyte-stimulating hormone release-inhibiting factor (MIF) and purified MIF prepared from bovine hypothalami induces arginine vasotocin release into cerebrospinal fluid of cats and significantly decreases the pineal arginine vasotocin content at 5 minutes after the injection. The present results demonstrate an extrapituitary endocrine effect of synthetic and purified bovine MIF.

摘要

向猫的颈动脉内注射合成的促黑素细胞激素释放抑制因子（MIF）以及从牛下丘脑制备的纯化MIF，均可诱导精氨酸血管催产素释放到脑脊液中，并在注射后5分钟时显著降低松果体中精氨酸血管催产素的含量。目前的结果证明了合成的和纯化的牛MIF的垂体外内分泌作用。