Fanchon Laurent, Grandjean Dominique
Unité de Médecine de l'Elevage et du Sport, Ecole Nationale Vétérinaire d'Alfort, 94700 Maisons, Alfort, France.
Am J Vet Res. 2007 Oct;68(10):1089-94. doi: 10.2460/ajvr.68.10.1089.
To determine the accuracy of asymmetry indices of ground reaction forces (GRF) for diagnosis of hind limb lameness in dogs.
36 healthy dogs and 13 dogs with naturally acquired cranial cruciate ligament rupture or hip dysplasia.
Lameness for affected dogs ranged from not detectable to minor and constant. While dogs trotted on an instrumented treadmill, GRF variables were recorded and analyzed with asymmetry indices. Each index was tested for its ability to discriminate between healthy and affected dogs. Combinations of several indices were also assessed.
Vertical force variables had better accuracy than craniocaudal force variables. Peak vertical force was the most accurate variable. Partial asymmetry during trotting was detected in healthy dogs. A multivariate approach that used peak vertical force and maximal rising slope yielded the optimum combination to distinguish between healthy and affected dogs. In addition, sensitivity of 92% or specificity of 95% may be achieved with 2 cutoff values while simultaneously maintaining specificity or sensitivity, respectively, at > 85%.
Asymmetry indices of GRFs were accurate for detection of hind limb lameness in dogs. This is particularly relevant for study designs in which only a single gait evaluation is possible.
确定地面反作用力(GRF)不对称指数对犬后肢跛行诊断的准确性。
36只健康犬和13只自然发生颅交叉韧带断裂或髋关节发育不良的犬。
患犬的跛行程度从不可检测到轻微且持续不等。当犬在装有仪器的跑步机上小跑时,记录GRF变量并用不对称指数进行分析。测试每个指数区分健康犬和患犬的能力。还评估了几个指数的组合。
垂直力变量比头尾向力变量具有更高的准确性。峰值垂直力是最准确的变量。在健康犬中检测到小跑时的部分不对称。使用峰值垂直力和最大上升斜率的多变量方法产生了区分健康犬和患犬的最佳组合。此外,在分别保持特异性或敏感性>85%的同时,通过2个临界值可实现92%的敏感性或95%的特异性。
GRF的不对称指数对犬后肢跛行的检测准确。这对于仅能进行单一步态评估的研究设计尤为重要。