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弹性髓内钉及脱钙骨基质-骨髓注射治疗单纯性骨囊肿

Elastic intramedullary nailing and DBM-bone marrow injection for the treatment of simple bone cysts.

作者信息

Kanellopoulos Anastasios D, Mavrogenis Andreas F, Papagelopoulos Panayiotis J, Soucacos Panayotis N

机构信息

First Department of Orthopaedics, Athens University Medical School, Athens Greece.

出版信息

World J Surg Oncol. 2007 Oct 4;5:111. doi: 10.1186/1477-7819-5-111.

Abstract

BACKGROUND

Simple or unicameral bone cysts are common benign fluid-filled lesions usually located at the long bones of children before skeletal maturity.

METHODS

We performed demineralized bone matrix and iliac crest bone marrow injection combined with elastic intramedullary nailing for the treatment of simple bone cysts in long bones of 9 children with a mean age of 12.6 years (range, 4 to 15 years).

RESULTS

Two of the 9 patients presented with a pathological fracture. Three patients had been referred after the failure of previous treatments. Four patients had large lesions with impending pathological fractures that interfered with daily living activities. We employed a ratio to ascertain the severity of the lesion. The extent of the lesion on the longitudinal axis was divided with the normal expected diameter of the long bone at the site of the lesion. The mean follow-up was 77 months (range, 5 to 8 years). All patients were pain free and had full range of motion of the adjacent joints at 6 weeks postoperatively. Review radiographs showed that all 7 cysts had consolidated completely (Neer stage I) and 2 cysts had consolidated partially (Neer stage II). Until the latest examination there was no evidence of fracture or re-fracture.

CONCLUSION

Elastic intramedullary nailing has the twofold benefits of continuous cyst decompression, and early immediate stability to the involved bone segment, which permits early mobilization and return to the normal activities of the pre-teen patients.

摘要

背景

单纯性或单房性骨囊肿是常见的良性充满液体的病变,通常位于骨骼成熟前儿童的长骨。

方法

我们对9名平均年龄为12.6岁(范围4至15岁)的儿童长骨单纯性骨囊肿患者进行了脱矿骨基质和髂嵴骨髓注射联合弹性髓内钉治疗。

结果

9例患者中有2例出现病理性骨折。3例患者在先前治疗失败后前来就诊。4例患者有大的病变且即将发生病理性骨折,影响日常生活活动。我们采用一个比值来确定病变的严重程度。病变在纵轴上的范围除以病变部位长骨的正常预期直径。平均随访77个月(范围5至8年)。所有患者术后6周均无疼痛,相邻关节活动范围正常。复查X线片显示,7个囊肿全部愈合(Neer I期),2个囊肿部分愈合(Neer II期)。直至最近一次检查,均无骨折或再骨折的证据。

结论

弹性髓内钉具有双重益处,即持续囊肿减压以及对受累骨段早期即刻稳定,这使得青少年患者能够早期活动并恢复正常活动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/984d/2117015/217d7905676f/1477-7819-5-111-1.jpg

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