De Boer R J
Bioinformatica, University of Utrecht, The Netherlands.
Neth J Med. 1991 Oct;39(3-4):254-62.
A recent class of mathematical models of the immune network is reviewed. The models in this class are based upon the bell-shaped activation function that is known to be characteristic for receptor cross-linking. These network models have a large number of self-regulatory properties. This review discusses of number of these properties, i.e. immunological memory, suppression, and repertoire selection.
本文综述了近期一类免疫网络的数学模型。这类模型基于钟形激活函数,该函数是受体交联的特征。这些网络模型具有大量的自我调节特性。本综述讨论了其中一些特性,即免疫记忆、抑制和库选择。