针对功能性腹痛或肠易激综合征儿童的催眠疗法:一项随机对照试验。
Hypnotherapy for children with functional abdominal pain or irritable bowel syndrome: a randomized controlled trial.
作者信息
Vlieger Arine M, Menko-Frankenhuis Carla, Wolfkamp Simone C S, Tromp Ellen, Benninga Marc A
机构信息
Department of Pediatrics, St. Antonius Hospital, Nieuwegein, The Netherlands.
出版信息
Gastroenterology. 2007 Nov;133(5):1430-6. doi: 10.1053/j.gastro.2007.08.072. Epub 2007 Sep 2.
BACKGROUND & AIMS: Functional abdominal pain (FAP) and irritable bowel syndrome (IBS) are highly prevalent in childhood. A substantial proportion of patients continues to experience long-lasting symptoms. Gut-directed hypnotherapy (HT) has been shown to be highly effective in the treatment of adult IBS patients. We undertook a randomized controlled trial and compared clinical effectiveness of HT with standard medical therapy (SMT) in children with FAP or IBS.
METHODS
Fifty-three pediatric patients, age 8-18 years, with FAP (n = 31) or IBS (n = 22), were randomized to either HT or SMT. Hypnotherapy consisted of 6 sessions over a 3-month period. Patients in the SMT group received standard medical care and 6 sessions of supportive therapy. Pain intensity, pain frequency, and associated symptoms were scored in weekly standardized abdominal pain diaries at baseline, during therapy, and 6 and 12 months after therapy.
RESULTS
Pain scores decreased significantly in both groups: from baseline to 1 year follow-up, pain intensity scores decreased in the HT group from 13.5 to 1.3 and in the SMT group from 14.1 to 8.0. Pain frequency scores decreased from 13.5 to 1.1 in the HT group and from 14.4 to 9.3 in the SMT group. Hypnotherapy was highly superior, with a significantly greater reduction in pain scores compared with SMT (P < .001). At 1 year follow-up, successful treatment was accomplished in 85% of the HT group and 25% of the SMT group (P < .001).
CONCLUSIONS
Gut-directed HT is highly effective in the treatment of children with longstanding FAP or IBS.
背景与目的
功能性腹痛(FAP)和肠易激综合征(IBS)在儿童中极为常见。相当一部分患者的症状会持续很长时间。肠道导向催眠疗法(HT)已被证明对成年IBS患者的治疗非常有效。我们进行了一项随机对照试验,比较了HT与标准药物治疗(SMT)对患有FAP或IBS儿童的临床疗效。
方法
53名年龄在8至18岁之间的儿科患者,其中FAP患者31例,IBS患者22例,被随机分为HT组或SMT组。催眠疗法在3个月内进行6次疗程。SMT组的患者接受标准医疗护理和6次支持性治疗。在基线、治疗期间以及治疗后6个月和12个月时,通过每周标准化的腹痛日记对疼痛强度、疼痛频率及相关症状进行评分。
结果
两组的疼痛评分均显著降低:从基线到1年随访,HT组的疼痛强度评分从13.5降至1.3,SMT组从14.1降至8.0。HT组的疼痛频率评分从13.5降至1.1,SMT组从14.4降至9.3。催眠疗法效果显著优于标准药物治疗,疼痛评分的降低幅度明显大于SMT组(P < .001)。在1年随访时,HT组85%的患者治疗成功,SMT组为25%(P < .001)。
结论
肠道导向催眠疗法对患有长期FAP或IBS的儿童治疗非常有效。