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与成人肾移植中“按需”置入支架相比,常规置入支架可减少泌尿系统并发症。

Routine stenting reduces urologic complications as compared with stenting "on demand" in adult kidney transplantation.

作者信息

Georgiev Panco, Böni Christian, Dahm Felix, Maurus Christine F, Wildi Stefan, Rousson Valentin, Wüthrich Rudolf P, Clavien Pierre-Alain, Weber Markus

机构信息

Department of Visceral and Transplant Surgery, University Hospital of Zurich, Zurich, Switzerland.

出版信息

Urology. 2007 Nov;70(5):893-7. doi: 10.1016/j.urology.2007.06.1100. Epub 2007 Oct 24.

Abstract

OBJECTIVES

To examine the impact of the chosen surgical technique and of systematic versus "on-demand" placement of a primary stent on the incidence of urologic complications in adult kidney transplantation.

METHODS

Data of 497 consecutive patients undergoing kidney transplantation at a single center were retrospectively analyzed with respect to urologic complications. Three different surgical strategies for the ureteroneocystostomy were compared: (1) transvesical anastomosis with stenting "on demand," (2) extravesical anastomosis with stenting "on demand," and (3) extravesical anastomosis with routine stenting. Nine parameters were evaluated by logistic regression for a possible contribution to the development of urologic complications.

RESULTS

Routine placement of a stent significantly reduced the number of urologic complications compared with both transvesical or extravesical anastomoses with stenting "on demand" (20.8% in transvesical "on demand," 17.9% in extravesical "on demand," and 5.8% in extravesical "routine"). Logistic regression analysis revealed that routine stenting versus stenting "on demand" (P = 0.001) and living donor transplantation (P = 0.038) are two independent factors associated with a significantly lower incidence of urologic complications. Although routine stenting was not associated with an increased incidence of urinary tract infections, female gender was the only independent factor associated with this complication (P = 0.001).

CONCLUSIONS

Routine stenting of the ureteroneocystostomy is superior to stenting "on demand" in adult kidney transplantation, suggesting that the intraoperative decision of whether to stent is insufficient to avoid urologic complications.

摘要

目的

探讨所选手术技术以及原发性支架系统放置与按需放置对成人肾移植泌尿系统并发症发生率的影响。

方法

回顾性分析在单一中心连续接受肾移植的497例患者的泌尿系统并发症数据。比较了输尿管膀胱吻合术的三种不同手术策略:(1)经膀胱吻合术并按需放置支架;(2)膀胱外吻合术并按需放置支架;(3)膀胱外吻合术并常规放置支架。通过逻辑回归评估九个参数对泌尿系统并发症发生的可能影响。

结果

与经膀胱或膀胱外吻合术并按需放置支架相比,常规放置支架显著减少了泌尿系统并发症的数量(经膀胱按需放置为20.8%,膀胱外按需放置为17.9%,膀胱外常规放置为5.8%)。逻辑回归分析显示,常规放置支架与按需放置支架(P = 0.001)以及活体供体移植(P = 0.038)是与泌尿系统并发症发生率显著降低相关的两个独立因素。虽然常规放置支架与尿路感染发生率增加无关,但女性是与该并发症相关的唯一独立因素(P = 0.001)。

结论

在成人肾移植中,输尿管膀胱吻合术常规放置支架优于按需放置支架,这表明术中关于是否放置支架的决策不足以避免泌尿系统并发症。

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