Krsiak M
Institute of Pharmacology, Czechoslovak Academy of Sciences, Prague.
Neurosci Biobehav Rev. 1991 Winter;15(4):439-45. doi: 10.1016/s0149-7634(05)80124-1.
Ethopharmacology can be defined as the study of behavioral and other effects of drugs through the use of ethological concepts. The study of drug effects on natural action patterns (motor acts and postures listed in ethograms), with respect to natural settings and to behavior as a whole (all identifiable behaviors occurring during the measurement) represents the basic concepts of ethopharmacology. Although pioneers drew attention to the potential of the ethological approach in pharmacology in the early 1960s, the number of publications utilizing this approach has steadily grown only since the mid-1970s. In the 1980s, modern technology, such as videorecorders, microcomputers and software, has been more widely applied in ethopharmacological experiments, greatly facilitating the observation and quantitative analysis of multiple data. Ethopharmacology is not "another" behavioral pharmacology, but an integral part of it. Rather, it represents one of the tools which can be useful (and sometimes even indispensable) in achieving a better understanding of the behavioral effects of drugs. It is to be hoped that it will be used in concert with other approaches in the future.
行为药理学可以被定义为通过运用行为学概念来研究药物的行为及其他效应。研究药物对自然行为模式(行为图谱中列出的运动行为和姿势)的影响,涉及自然环境以及整体行为(测量过程中出现的所有可识别行为),这代表了行为药理学的基本概念。尽管在20世纪60年代早期,先驱者们就已关注到行为学方法在药理学中的潜力,但直到20世纪70年代中期,采用这种方法的出版物数量才稳步增长。在20世纪80年代,诸如录像机、微型计算机和软件等现代技术在行为药理学实验中得到了更广泛的应用,极大地促进了对多个数据的观察和定量分析。行为药理学并非“另一种”行为药理学,而是其不可或缺的一部分。相反,它是一种工具,有助于(有时甚至是必不可少的)更好地理解药物的行为效应。希望未来它能与其他方法协同使用。