Olivier B, Rasmussen D, Raghoebar M, Mos J
Department of Pharmacology, Duphar B.V., Weesp, The Netherlands.
Drug Metabol Drug Interact. 1990;8(1-2):11-29. doi: 10.1515/dmdi.1990.8.1-2.11.
The present contribution describes the basic fundamentals of animal models in ethopharmacology. After defining the role of ethopharmacology in the development of animal models of relevant human diseases, this methodology is used to classify different categories of aggression. Furthermore, the behavioural aspects of agonistic (aggressive) modelling are outlined and the various models used to describe offensive and defensive behaviours, and some miscellaneous models are summarized. Finally, some remarks on the new class of psychoactive drugs, serenics, are given.
本论文阐述了行为药理学中动物模型的基本原理。在明确行为药理学在相关人类疾病动物模型开发中的作用后，该方法被用于对不同类型的攻击行为进行分类。此外，还概述了攻击性建模的行为学方面，总结了用于描述进攻和防御行为的各种模型以及一些其他模型。最后，对新型精神活性药物——安定药进行了一些评论。
