Lovecchio Frank, Cannon Robert D, Algier Jeffrey, Ruha Anne-Marie, Curry Steven C, Wallace Kevin L, Graeme Kimberley A
Department of Medical Toxicology and Banner Good Samaritan Regional Poison Center, Phoenix, AZ, USA.
Am J Emerg Med. 2007 Oct;25(8):931-3. doi: 10.1016/j.ajem.2007.02.006.
Africanized honeybees (Apis mellifera scutellata) are now found in the southern and southwestern United States. Swarmings can result in hundreds to thousands of stings delivering a venom load capable of producing multisystem organ failure and death. The literature on mass envenomations is scarce, being limited to case reports and case series. There are no prospective studies on mass envenomations in children.
All patients were admitted to our toxicology service, and all stingers were counted. Laboratory data and clinical assessments were obtained at baseline, 8, and 16 hours after presentation.
Nineteen patients with a median age of 3.6 years and a median of 2.64 stings per kilogram (range, 1-4.5) were enrolled. Fifteen children had vomiting. Only a mild increase in creatine kinase was seen. None developed coagulopathy or renal insufficiency.
Envenomations of up to 4.5 stings per kilogram resulted in only mild systemic illness. Vomiting does not portend involvement of other organ systems.
非洲化蜜蜂(Apis mellifera scutellata)如今在美国南部和西南部被发现。蜂群迁移可能导致数百至数千次蜇刺,注入的毒液量足以引发多系统器官衰竭甚至死亡。关于大规模蜂蜇中毒的文献稀少,仅限于病例报告和病例系列。目前尚无针对儿童大规模蜂蜇中毒的前瞻性研究。
所有患者均入住我们的毒理学科室,并统计所有蜇刺数量。在就诊时、8小时和16小时获取实验室数据和临床评估结果。
纳入了19名患者,中位年龄为3.6岁,中位蜇刺数为每千克2.64次(范围为1 - 4.5次)。15名儿童出现呕吐症状。仅观察到肌酸激酶轻度升高。无人出现凝血病或肾功能不全。
每千克多达4.5次的蜇刺中毒仅导致轻微的全身症状。呕吐并不预示其他器官系统受累。