El Sakka Karim, Halawa Mustafa, Kotze Carl, Francis Ian, Doyle Tim, Yusuf Waquar
Department of Vascular and Endovascular Surgery, Brighton and Sussex University Hospital, UK.
Interact Cardiovasc Thorac Surg. 2008 Feb;7(1):121-4. doi: 10.1510/icvts.2007.162982. Epub 2007 Oct 6.
Aorto-enteric fistulas (AEFs) and para-anastomotic aneurysms (PAAs) are uncommon complications of open aortic surgery (0.5-2.5%) and (0.2-15%), respectively. AEF if untreated is often fatal and surgical management is associated with mortality up to 90%. The risk of PAA rupture carries a mortality of 58%. We present our experience in ten patients with the endovascular treatment of these complications to define the role of endovascular repair in this high-risk group.
This is a retrospective review of patients presenting acutely with complications of open aortic surgery. From January 2003 to March 2006, ten patients, all males with a mean age of 73 years presented through the Accident and Emergency department and were assessed with contrast enhanced CT. Five patients presented with secondary AEFs. Three patients with PAAs. Another patient presented with a secondary mycotic aneurysm of the thoracic aorta following open repair of abdominal aortic aneurysm and finally a patient with a femoral pseudoaneurysm. The mean time from the original procedure to presentation was 50 months. All patients were offered endovascular management after stabilisation as they were deemed as high-risk surgical patients.
No intra-procedural complications were recorded. The in-hospital 30-day mortality was 1 (10%) patient due to multiple organ failure. One patient died six months later due to an unrelated event. The average in-hospital stay was 5.4 days; median follow-up period was 28 months. All patients were repeatedly admitted after discharge due to septic episodes for which they received IV antibiotics. Repeated cultures for all patients were only positive on four occasions.
Endovascular stent-graft repair of AEF and PAAs is a viable alternative to open surgery. It is likely to be associated with less mortality and morbidity and in-hospital stay. It should be considered as an alternative in high-risk patients. Persistence of the infection remains a problem, however, in our experience; it can be well controlled through long-term antibiotics.
主动脉肠瘘(AEF)和吻合口旁动脉瘤(PAA)分别是开放性主动脉手术不常见的并发症(发生率为0.5 - 2.5%)和(发生率为0.2 - 15%)。AEF若不治疗往往致命,手术治疗的死亡率高达90%。PAA破裂的风险死亡率为58%。我们介绍对10例这些并发症患者进行血管腔内治疗的经验,以明确血管腔内修复在这一高危组中的作用。
这是一项对急性出现开放性主动脉手术并发症患者的回顾性研究。2003年1月至2006年3月,10例患者,均为男性,平均年龄73岁,通过急诊科就诊,并接受了增强CT评估。5例患者为继发性AEF。3例患者为PAA。另一例患者在腹主动脉瘤开放修复术后出现胸主动脉继发性真菌性动脉瘤,最后1例患者为股部假性动脉瘤。从初次手术到出现并发症的平均时间为50个月。所有患者在病情稳定后均被视为高危手术患者而接受血管腔内治疗。
未记录到术中并发症。30天内住院死亡率为1例(10%),死于多器官功能衰竭。1例患者6个月后因无关事件死亡。平均住院时间为5.4天;中位随访期为28个月。所有患者出院后因脓毒症发作多次入院,为此接受了静脉抗生素治疗。所有患者的重复培养仅4次呈阳性。
血管腔内支架移植物修复AEF和PAA是开放性手术的可行替代方案。它可能与较低的死亡率、发病率和住院时间相关。在高危患者中应将其视为一种替代方案。然而,在我们的经验中,感染持续存在仍是一个问题;通过长期使用抗生素可得到良好控制。