Infantile acropustulosis.

Infantile acropustulosis is a recurrent, pruritic, vesicopustular eruption appearing mostly on the palms and soles. The present survey of 25 children with infantile acropustulosis is the most extensive reported since this entity was first described in 1979. Our cases conform to the recognized clinical course, but disclaim any male or ethnic origin predominance. Although the etiology of infantile acropustulosis is obscure, it may be ascribed to some infective agent. It is not limited to young children, and has been found in the siblings of patients who were followed. Suppressive therapeutic measures, such as topical corticosteroids under occlusion, were found to be effective. The disorder does not seem to be as rare as one might gather from the literature.