May Matthias, Gralla Oliver, Knoll Nina, Fenske Stephan, Spivak Inna, Rönnebeck Claudia, Hoffmann Marga, Lenk Severin, Hoschke Bernd
Department of Urology, Carl-Thiem Hospital, Cottbus, Germany.
BJU Int. 2007 Nov;100(5):1110-5. doi: 10.1111/j.1464-410X.2007.07101.x.
To investigate the age-stratified prevalence of erectile dysfunction (ED) and its comorbidities, and to assess the population's knowledge, utilization, and general attitude towards the treatment for ED.
In all, 10 000 men received a 35-item questionnaire including the International Index of Erectile Function (IIEF) and sociodemographic questions regarding life style, comorbidities, quality of sexual life and knowledge or experience of ED therapy. In all, 3124 responses were included (31.2%), 2499 men lived in well established partnerships and were assessed as the basic study group.
In the entire population the prevalence rate of ED was 40.1%. However, although known, medical treatment for ED is used only by a minority of affected men. The prevalence of ED was independently associated with age, peripheral arterial occlusive disease, hypertension, ischaemic heart disease, diabetes mellitus, and liver diseases. Correlations between sexual quality of life (QoL) and ED were statistically significant (P < 0.01) and moderate to strong (absolute values: Spearman's rho 0.35-0.76). Although 96% of the study population knew at least one phosphodiesterase type 5 (PDE5) inhibitor by name, only 53% considered taking the medication and only 9% of the men with ED had had experience with available PDE5 inhibitors.
The sexual QoL was significantly reduced by ED. Despite high levels of awareness and general acceptance of oral medication for ED, experience with PDE5 inhibitors was low. Further investigation is required to evaluate the general impact of ED on sexual QoL and the need or wish for treatment.
调查勃起功能障碍(ED)及其合并症的年龄分层患病率,并评估人群对ED治疗的认知、利用情况及总体态度。
共10000名男性接受了一份包含35个条目的问卷,问卷内容包括国际勃起功能指数(IIEF)以及关于生活方式、合并症、性生活质量和ED治疗知识或经验的社会人口学问题。总共纳入3124份回复(31.2%),2499名处于稳定伴侣关系的男性被评估为基础研究组。
在整个人群中,ED的患病率为40.1%。然而,尽管ED的药物治疗是已知的,但只有少数受影响的男性使用。ED的患病率与年龄、外周动脉闭塞性疾病、高血压、缺血性心脏病、糖尿病和肝脏疾病独立相关。性生活质量(QoL)与ED之间的相关性具有统计学意义(P<0.01),且为中度至高度相关(绝对值:Spearman等级相关系数0.35 - 0.76)。尽管96%的研究人群至少知道一种5型磷酸二酯酶(PDE5)抑制剂的名称,但只有53%的人考虑服用该药物,且只有9%的ED男性有使用现有PDE5抑制剂的经验。
ED显著降低了性生活质量。尽管对ED口服药物的知晓率和总体接受度较高,但PDE5抑制剂的使用经验较少。需要进一步调查以评估ED对性生活质量的总体影响以及治疗的需求或意愿。