Mariappan Paramananthan, Chong Wooi Loong
Department of Urology, Western General Hospital, Edinburgh, UK.
BJU Int. 2006 Dec;98(6):1264-8. doi: 10.1111/j.1464-410X.2006.06525.x. Epub 2006 Oct 11.
To determine, in a population-based survey, the prevalence of lower urinary tract symptoms (LUTS), erectile dysfunction (ED) and incontinence in community-dwelling men in multiethnic Malaysia, as currently available Western demographic data might not be applicable in the Asian population.
A cross-sectional population-based survey was carried out in the State of Penang, Malaysia, with a target population of men aged > or = 40 years. Using a multistage study design, random systematic sampling was used to represent the target population, who were weighted based on ethnicity and rural-urban ratios so as to represent the general population distribution. Trained field-workers conducted direct interviews and administered the American Urological Association Symptom Index (AUA-SI), the International Index of Erectile Function (IIEF-5) questionnaire and questions on incontinence based on the International Continence Society 2002 definition.
In all, 418 men aged > or = 40 years were interviewed, of whom 353 completed the AUA-SI questionnaire (84.5% response rate). The prevalence of mild, moderate and severe LUTS was 80.6%, 6% and 0.3%, respectively. The prevalent symptoms were frequency and nocturia. There was moderate and severe ED in 45.9% of men, whereas incontinence was reported by 8.2%. The AUA-SI correlated strongly with age (R = 0.291, P < 0.001), IIEF-5 (R = - 0.265, P < 0.001) and diabetes mellitus.
The prevalence and severity of LUTS, ED and incontinence increased with age in this multiethnic Asian population, in which ED correlated strongly with LUTS. Compared to the Western population, the prevalence of LUTS was significantly lower, while the prevalence of ED and incontinence were comparable.
在一项基于人群的调查中,确定马来西亚多民族社区居住男性下尿路症状(LUTS)、勃起功能障碍(ED)和尿失禁的患病率,因为目前可用的西方人口数据可能不适用于亚洲人群。
在马来西亚槟城州进行了一项基于人群的横断面调查,目标人群为年龄≥40岁的男性。采用多阶段研究设计,使用随机系统抽样来代表目标人群,并根据种族和城乡比例进行加权,以代表总体人群分布。训练有素的现场工作人员进行直接访谈,并发放美国泌尿外科学会症状指数(AUA-SI)、国际勃起功能指数(IIEF-5)问卷以及基于国际尿失禁学会2002年定义的尿失禁相关问题。
总共对418名年龄≥40岁的男性进行了访谈,其中353人完成了AUA-SI问卷(应答率为84.5%)。轻度、中度和重度LUTS的患病率分别为80.6%、6%和0.3%。常见症状为尿频和夜尿。45.9% 的男性存在中度和重度ED,而8.2% 的男性报告有尿失禁。AUA-SI与年龄(R = 0.291,P < 0.001)、IIEF-5(R = - 0.265,P < 0.001)和糖尿病密切相关。
在这个多民族亚洲人群中,LUTS、ED和尿失禁的患病率及严重程度随年龄增加,其中ED与LUTS密切相关。与西方人群相比,LUTS的患病率显著较低,而ED和尿失禁的患病率相当。