鸦片与冠状动脉疾病的关联。
The association of opium with coronary artery disease.
作者信息
Sadeghian Saeed, Darvish Soodabeh, Davoodi Gholamreza, Salarifar Mojtaba, Mahmoodian Mehran, Fallah Nader, Karimi Abbas Ali
机构信息
Tehran Heart Center, Tehran University of Medical Sciences, Jalal AL-Ahmad & North Kargar Cross, Tehran, Iran.
出版信息
Eur J Cardiovasc Prev Rehabil. 2007 Oct;14(5):715-7. doi: 10.1097/HJR.0b013e328045c4e9.
BACKGROUND
The effects of opium consumption on coronary artery disease are still unknown.
METHODS
A cross-sectional study was conducted on 2405 patients admitted to the Angiographic Ward at Tehran Heart Center from 7 May 2005 to 13 August 2005.
RESULTS
After adjusting for conventional cardiovascular risk factors, opium consumption was a significant risk factor for coronary artery disease (P=0.01 and odds ratio=1.8). Moreover, the amount of opium consumption was associated significantly with the severity of coronary atherosclerosis, as measured by clinical vessel score (r=0.2, P=0.002).
CONCLUSIONS
To our knowledge, this is the first time that the adverse effects of opium consumption on coronary arteries was defined.
背景
吸食鸦片对冠状动脉疾病的影响尚不清楚。
方法
对2005年5月7日至2005年8月13日入住德黑兰心脏中心血管造影病房的2405例患者进行了横断面研究。
结果
在对传统心血管危险因素进行校正后，吸食鸦片是冠状动脉疾病的一个显著危险因素（P=0.01，比值比=1.8）。此外，通过临床血管评分衡量，鸦片吸食量与冠状动脉粥样硬化的严重程度显著相关（r=0.2，P=0.002）。
结论
据我们所知，这是首次明确吸食鸦片对冠状动脉的不良影响。
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