使用串联烯烃交叉复分解/烯丙基碳酸酯还原序列的一锅法末端烯烃同系化反应。

One-pot terminal alkene homologation using a tandem olefin cross-metathesis/allylic carbonate reduction sequence.

作者信息

Comins Daniel L, Dinsmore Jason M, Marks Lucas R

机构信息

Department of Chemistry, North Carolina State University, Raleigh, NC, USA.

出版信息

Chem Commun (Camb). 2007 Oct 28(40):4170-1. doi: 10.1039/b709754a. Epub 2007 Aug 7.

DOI:10.1039/b709754a

PMID:17925965

Abstract

A one-carbon homologation of terminal alkenes has been developed utilizing an olefin cross-metathesis followed by a palladium-mediated allylic carbonate reduction; various substrates were used to demonstrate the scope of the reaction, with yields ranging from 65 to 86%.

摘要

利用烯烃交叉复分解反应，随后进行钯介导的烯丙基碳酸酯还原反应，开发了一种末端烯烃的一碳同系化反应；使用了各种底物来证明该反应的适用范围，产率在65%至86%之间。