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通过Suzuki-Miyaura 交叉偶联和烯烃复分解反应作为关键步骤，采用多样性导向方法合成大环环芳衍生物。

Diversity-oriented approach to macrocyclic cyclophane derivatives by Suzuki-Miyaura cross-coupling and olefin metathesis as key steps.

机构信息

Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai-400076 India.

出版信息

J Org Chem. 2012 Jan 6;77(1):482-9. doi: 10.1021/jo2020714. Epub 2011 Dec 13.

DOI:10.1021/jo2020714
PMID:22129223
Abstract

Palladium-catalyzed Suzuki-Miyaura (SM) cross-coupling reaction with allylboronic acid pinacol ester and titanium assisted cross-metathesis (CM)/ring-closing metathesis (RCM) cascade has been used to synthesize macrocyclic cyclophane derivatives.

摘要

钯催化的Suzuki-Miyaura (SM) 交叉偶联反应与烯丙基硼酸频哪醇酯和钛辅助交叉复分解 (CM)/闭环复分解 (RCM) 级联反应已被用于合成大环环芳衍生物。

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