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[采用经血液吸附剂处理的自身输血法治疗消化性溃疡期间胃黏膜的临床形态学特征]

[The clinico-morphological characteristics of the gastric mucosa during peptic ulcer therapy with the autotransfusion of hemosorbent-treated blood].

作者信息

Zhidkov K P, Nutfullina G M

出版信息

Ter Arkh. 1991;63(8):81-4.

PMID:1792626
Abstract

A study was made of gastric biopsy specimens withdrawn on repeated endoscopy in 35 patients with chronic gastric ulcers before and 2 weeks after the treatment by autohemotransfusion of hemosorbent-treated blood (AHTB). In 30 patients, the ulcer healed or reduced in size, in 5 patients, the effect was lacking. Morphologic and morphometric studies were carried out on cryostat sections stained by means of PAS and according to Romanovsky-Giemsa. They involved determination of the specific area of the gland and count of free cells of the stroma surrounding the gland followed by an analysis of correlations between effector cells of the immune system. A comprehensive estimation of the accumulation and distribution of the cells infiltrating m. mucosae of the stomach and of their interaction revealed the dependence on the use of AHTB.

摘要

对35例慢性胃溃疡患者在采用血液吸附剂处理过的血液进行自血回输治疗(AHTB)之前及治疗后2周重复进行内镜检查时获取的胃活检标本进行了研究。30例患者的溃疡愈合或缩小,5例患者无效。对经PAS染色及罗曼诺夫斯基-吉姆萨染色的低温恒温器切片进行了形态学和形态计量学研究。研究包括确定腺体的特定面积以及计数腺体周围基质中的游离细胞,随后分析免疫系统效应细胞之间的相关性。对浸润胃黏膜肌层的细胞的聚集和分布及其相互作用进行的综合评估揭示了其对AHTB使用的依赖性。

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