van den Ende J, Kloppers L L, Hyland J, Lennon M E
S Afr Med J. 1977 May 28;51(22):800-2.
Crebrospinal fluid (CSF) from 142 patients was tested for the presence of Haemophilus influenzae, pneumococcal and meningococcal antigens by counter-immuno-electrophoresis with commercial antisera. Group- or type-specific antigen was detected in the CSF of 67% of 64 patients with meningitis proved by culture to be due to these organisms, and in 10 of 25 patients with purulent meningitis but negative cultures. No false positive results were obtained in 24 normal CSF specimens, or in the CSF of 29 patients with meningitis caused by other organisms. The diagnostic usefulness of this specific, relatively simple and rapid procedure is confirmed.
采用市售抗血清，通过对流免疫电泳法对142例患者的脑脊液（CSF）进行了流感嗜血杆菌、肺炎球菌和脑膜炎球菌抗原检测。在64例经培养证实由这些病原体引起脑膜炎的患者中，67%的患者脑脊液中检测到群特异性或型特异性抗原；在25例化脓性脑膜炎但培养结果为阴性的患者中，有10例检测到相应抗原。24份正常脑脊液标本以及29例由其他病原体引起脑膜炎患者的脑脊液中均未获得假阳性结果。这一特异、相对简单且快速的检测方法的诊断价值得到了证实。
