Salo Ruth, Nordahl Thomas E, Leamon Martin H, Natsuaki Yutaka, Moore Charles D, Waters Christy, Carter Cameron S
Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA.
Psychiatry Res. 2008 Jan 15;157(1-3):273-7. doi: 10.1016/j.psychres.2007.04.018. Epub 2007 Oct 24.
The goal of this study was to examine behavioral characteristics of currently drug-abstinent methamphetamine (MA)-dependent subjects (n=39) who experienced psychotic symptoms associated with MA abuse. All participants completed the Wender Utah Rating Scale (WURS), which retrospectively assesses Attention Deficit Hyperactivity Disorder-relevant childhood behaviors. The results suggest the existence of possible behavioral markers reflecting an early cognitive vulnerability to the development of frequent MA-induced psychotic symptoms as well as increased vulnerability associated with a family history of psychiatric illness.
本研究的目的是检查目前已戒除毒品的甲基苯丙胺(MA)依赖者(n = 39)的行为特征,这些依赖者曾经历过与甲基苯丙胺滥用相关的精神病症状。所有参与者都完成了温德犹他评定量表(WURS),该量表可回顾性评估与注意缺陷多动障碍相关的儿童期行为。结果表明,可能存在行为标志物,反映出对频繁的甲基苯丙胺诱发的精神病症状发展的早期认知易感性,以及与精神疾病家族史相关的易感性增加。