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基于工作流的生命科学信息学框架。

Workflow based framework for life science informatics.

作者信息

Tiwari Abhishek, Sekhar Arvind K T

机构信息

Informatics Division, GVK Biosciences, Hyderabad 500037, India.

出版信息

Comput Biol Chem. 2007 Oct;31(5-6):305-19. doi: 10.1016/j.compbiolchem.2007.08.009. Epub 2007 Aug 19.

Abstract

Workflow technology is a generic mechanism to integrate diverse types of available resources (databases, servers, software applications and different services) which facilitate knowledge exchange within traditionally divergent fields such as molecular biology, clinical research, computational science, physics, chemistry and statistics. Researchers can easily incorporate and access diverse, distributed tools and data to develop their own research protocols for scientific analysis. Application of workflow technology has been reported in areas like drug discovery, genomics, large-scale gene expression analysis, proteomics, and system biology. In this article, we have discussed the existing workflow systems and the trends in applications of workflow based systems.

摘要

工作流技术是一种通用机制,用于整合各种类型的可用资源(数据库、服务器、软件应用程序和不同服务),这有助于在传统上不同的领域(如分子生物学、临床研究、计算科学、物理学、化学和统计学)内进行知识交流。研究人员可以轻松地整合和访问各种分布式工具和数据,以开发自己的科学分析研究方案。工作流技术已在药物发现、基因组学、大规模基因表达分析、蛋白质组学和系统生物学等领域得到应用。在本文中,我们讨论了现有的工作流系统以及基于工作流的系统的应用趋势。

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