抗生素经奥美定在体外及烧伤患者的中厚皮片上的渗透情况。

Penetration of antibiotics through omiderm in vitro and on split-thickness skin grafts in burn patients.

作者信息

Russavage J M, Slater H, Goldfarb I W, Hammell E J

机构信息

General Surgery Department, University of Pittsburgh, Presbyterian University Hospital, PA.

出版信息

Ann Plast Surg. 1991 Dec;27(6):559-61. doi: 10.1097/00000637-199112000-00008.

DOI:10.1097/00000637-199112000-00008

PMID:1793242

Abstract

Penetration of antibiotic preparations (gentamicin, neomycin, silver sulfadiazine, mupirocin) through Omiderm, a synthetic wound covering, was tested in vitro and in 5 patients with full-thickness burns who had undergone tangential excision and split-thickness skin grafting. All antibiotic preparations tested penetrated both meshed and unmeshed Omiderm. Omiderm did not affect the zones of inhibition of antimicrobial activity as compared with controls.

摘要

在体外以及对5例接受了削痂和中厚皮片移植的全层烧伤患者进行了测试，以检测抗生素制剂（庆大霉素、新霉素、磺胺嘧啶银、莫匹罗星）透过合成伤口覆盖物奥米德姆（Omiderm）的情况。所有测试的抗生素制剂均能穿透有网孔和无网孔的奥米德姆。与对照组相比，奥米德姆不影响抗菌活性的抑菌圈。