Greenberg Patty, Brown Jessica, Yates Teresa, Brown Vivian, Langenberg Patricia, Warren John W
Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
Neurourol Urodyn. 2008;27(4):287-90. doi: 10.1002/nau.20516.
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a symptom-based diagnosis. We studied the IC/PBS symptom commonly referred to as "urgency" and its relationship to IC/PBS pain in a group of women with recent onset of the disease.
As part of a case control study to identify risk factors for IC, cases completed a questionnaire including two statements regarding the perceived cause of their urge to void. One was related to fear of incontinence and the other was linked with relief of pain. A Likert scale indicating level of agreement/disagreement comprised the response options.
Most respondents (65%) agreed with the statement linking urge with pain relief. A minority (21%) concurred with the fear of incontinence statement. Disagreement for both was found in 19%. A substantial proportion (46%) agreed with pain relief but also disagreed that urge is related to fear of incontinence. Those who reported urge to relieve pain were significantly more likely to report worsened pain with bladder filling and/or improved pain with voiding. There were no such associations with urge to prevent incontinence. Overactive bladder or diabetes prior to IC onset did not confound these results.
At least two distinct experiences of urge to urinate are evident in this population. For most, urge is linked with pain relief and is associated with bladder filling/emptying. About 1/5 reported urge to prevent incontinence. A similar portion did not agree with either urge, indicating that they may experience something altogether different, which requires further inquiry.
间质性膀胱炎/疼痛性膀胱综合征（IC/PBS）是一种基于症状的诊断。我们在一组近期发病的女性患者中研究了IC/PBS中通常被称为“尿急”的症状及其与IC/PBS疼痛的关系。
作为一项旨在确定IC危险因素的病例对照研究的一部分，病例组完成了一份问卷，其中包括两条关于其排尿冲动感知原因的陈述。一条与对尿失禁的恐惧有关，另一条与疼痛缓解有关。回答选项采用李克特量表来表明同意/不同意的程度。
大多数受访者（65%）同意将尿急与疼痛缓解联系起来的陈述。少数人（21%）赞同与尿失禁恐惧有关的陈述。19%的人对两者均不同意。相当一部分人（46%）同意疼痛缓解，但不同意尿急与尿失禁恐惧有关。那些报告排尿冲动是为了缓解疼痛的人更有可能报告膀胱充盈时疼痛加剧和/或排尿时疼痛改善。尿急与预防尿失禁之间不存在此类关联。IC发病前的膀胱过度活动症或糖尿病并未混淆这些结果。
在这一人群中，至少有两种不同的尿急体验是明显的。对大多数人来说，尿急与疼痛缓解有关，且与膀胱充盈/排空相关。约五分之一的人报告尿急是为了预防尿失禁。类似比例的人对两种尿急情况均不同意，这表明他们可能经历了完全不同的情况，这需要进一步探究。
