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特发性体位性直立性心动过速综合征中的交感迷走神经平衡分析

Sympathovagal balance analysis in idiopathic postural orthostatic tachycardia syndrome.

作者信息

Russo Vincenzo, De Crescenzo Ilaria, Ammendola Ernesto, Santangelo Lucio, Calabrò Raffaele

机构信息

Second University of Naples, Monaldi Hospital, Naples, Italy.

出版信息

Acta Biomed. 2007 Aug;78(2):133-8.

Abstract

The idiopathic postural tachycardia syndrome (POTS) is a complex disorder characterized by chronic orthostatic symptoms and an increase in heart rate within 10 minutes of standing on upright posture, without significant orthostatic hypotension. We describe a case of a 36 year-old patient with POTS, diagnosed by head-up tilt testing. Power spectral analysis of heart rate variability (HRV), performed during the tilt test, revealed the ratio of low and high frequency powers (LF/HF) that increased with the onset of orthostatic intolerance. The increase in LF/HF power ratio may represent sympathetic beta-receptors hyperactivity. Atenolol alleviated his clinical symptoms.

摘要

特发性体位性心动过速综合征(POTS)是一种复杂的疾病,其特征为慢性体位性症状以及在直立姿势站立10分钟内心率增加,且无明显体位性低血压。我们描述了一例36岁患有POTS的患者,通过直立倾斜试验确诊。在倾斜试验期间进行的心率变异性(HRV)功率谱分析显示,低频和高频功率之比(LF/HF)随着体位性不耐受的发作而增加。LF/HF功率比的增加可能代表交感β受体功能亢进。阿替洛尔缓解了他的临床症状。

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