Kiziltan Meral E, Akalin M Ali, Sahin Rahsan, Uluduz Derya
Department of Neurology, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.
Neurosci Lett. 2007 Nov 12;427(3):138-41. doi: 10.1016/j.neulet.2007.09.029. Epub 2007 Sep 21.
The aim of this study is to evaluate the peripheral nerves in diabetes mellitus with or without peripheral facial paralysis (PFP). A total of 49 diabetic patients with PFP within the last year (23 females, mean age 60.3 +/- 9.3), and 83 diabetic patients without PFP (41 females, mean age 59.5 +/- 9.9) were enrolled. The neurological examination, eye-blinking response, needle EMG and electrophysiological parameters of peripheral nerves were evaluated. The neuropathic pain, other positive and negative sensory symptoms were statistically more frequent in controls than the PFP group, while no difference was noted in total neuropathy score. Sural sensorial nerve action potential amplitudes were same in both groups, but median nerve amplitudes were significantly lower in the PFP group. It is suggested that PFP is not a part of multifocal neuropathy in diabetes mellitus. However, at least some parts of the nerve conduction studies were involved, focal neuropathies were more frequent while sensory neuropathies with small nerve fiber involvement were less frequent in diabetes patients with PFP.
本研究的目的是评估患有或不患有周围性面瘫(PFP)的糖尿病患者的周围神经。共有49例在过去一年内患有PFP的糖尿病患者(23名女性,平均年龄60.3±9.3岁)和83例无PFP的糖尿病患者(41名女性,平均年龄59.5±9.9岁)被纳入研究。对周围神经的神经学检查、眨眼反应、针极肌电图和电生理参数进行了评估。对照组的神经性疼痛、其他阳性和阴性感觉症状在统计学上比PFP组更常见,而总神经病变评分无差异。两组的腓肠感觉神经动作电位幅度相同,但PFP组的正中神经幅度显著更低。提示PFP不是糖尿病多灶性神经病变的一部分。然而,至少部分神经传导研究涉及其中,在患有PFP的糖尿病患者中,局灶性神经病变更常见,而伴有小神经纤维受累的感觉神经病变则较少见。