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胸腔镜治疗食管闭锁合并远端瘘及气管软化症。

Thoracoscopic treatment of esophageal atresia with distal fistula and of tracheomalacia.

作者信息

van der Zee David C, Bax Klaas N M A

机构信息

Department of Pediatric Surgery, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands.

出版信息

Semin Pediatr Surg. 2007 Nov;16(4):224-30. doi: 10.1053/j.sempedsurg.2007.06.003.

Abstract

Single center experience with thoracoscopic repair of esophageal atresia with distal fistula and of tracheomalacia. Between May 2000 and December 2006, 51 neonates with an esophageal atresia were presented for thoracoscopic repair. Gestational age varied from 31 3/7 to 42 2/7 weeks (M = 37 2/7). Birth weight was between 1025 g and 4030 g (mean 2620 g). Concomitant anomalies or VACTERL association were encoutered in 31 patients (61%). Duration of the operation was from 90 minutes to 390 minutes (mean 178 minutes). All but 1 patient had an esophageal atresia with a distal fistula. Six patients had tracheomalacia requiring aortopexia, which was performed thoracoscopically. In 2 patients the thoracoscopic procedure had to be converted to a thoracotomy. All other patients underwent a successful thoracoscopic repair. One patient died in the postoperative period because of sepsis. A total of 22 patients (45%) developed a stenosis in the postoperative follow up (1 month-7y 7 month) requiring 1 to 18 dilatations (mean 1.5). Postoperative leakage occurred in 9 patients (18%). Recurrent fistula was encountered in 2 patients. A total of 11 patients (22%) underwent a laparoscopic antireflux procedure for either recurring stenosis (8) or ALTES (3). Six children (12%) underwent thoracoscopic aortopexy for tracheomalacia. In 2 children symptoms recurred for which a successful repeat thoracoscopic aortopexy was undertaken. The thoracoscopic approach to the treatment of esophageal atresia and tracheomalacia is becoming increasingly accepted. The cosmesis is undoubtedly better. The secundary effects like thoracic cage deformities, winged scapula, or scoliosis have not yet been described and are expected to be reduced in comparison to the open technique. Sequelae like leakage, stenosis, recurrent fistulae, and GERD and ALTES will probably remain the same. Whether thoracoscopic dissection has less detrimental effect on disturbed motility remains to be proven. Thoracoscopic aortopexy for severely symptomatic tracheomalacia is relatively simple. Even repeat thoracoscopic aortopexy is not that difficult. It was immediately effective in 2/3 of the patients.

摘要

食管闭锁合并远端瘘及气管软化症的单中心胸腔镜修复经验。2000年5月至2006年12月期间,51例食管闭锁新生儿接受了胸腔镜修复手术。孕周从31又3/7周到42又2/7周不等(平均37又2/7周)。出生体重在1025克至4030克之间(平均2620克)。31例患者(61%)合并有其他畸形或VACTERL综合征。手术时间从90分钟至390分钟不等(平均178分钟)。除1例患者外,所有患者均为食管闭锁合并远端瘘。6例患者有气管软化症,需要进行胸腔镜下主动脉固定术。2例患者的胸腔镜手术不得不转为开胸手术。所有其他患者均成功接受了胸腔镜修复。1例患者术后因败血症死亡。共有22例患者(45%)在术后随访(1个月至7年7个月)中出现狭窄,需要进行1至18次扩张(平均1.5次)。9例患者(18%)发生术后渗漏。2例患者出现复发性瘘。共有11例患者(22%)因复发性狭窄(8例)或食管气管瘘(3例)接受了腹腔镜抗反流手术。6例儿童(12%)因气管软化症接受了胸腔镜下主动脉固定术。2例儿童症状复发,成功进行了再次胸腔镜下主动脉固定术。胸腔镜治疗食管闭锁和气管软化症的方法越来越被接受。美容效果无疑更好。尚未描述如胸廓畸形、翼状肩胛或脊柱侧弯等继发效应,预计与开放技术相比会有所减少。如渗漏、狭窄、复发性瘘以及胃食管反流病和食管气管瘘等后遗症可能仍然存在。胸腔镜解剖对紊乱的运动功能是否有较小的有害影响仍有待证实。胸腔镜下主动脉固定术治疗严重症状性气管软化症相对简单。即使是再次胸腔镜下主动脉固定术也并非那么困难。2/3 的患者立即有效。

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