免疫病理学中的热休克蛋白

Heat shock proteins in immunopathology.

作者信息

Res P C, Thole J E, de Vries R R

机构信息

University Hospital, Leiden, The Netherlands.

出版信息

Curr Opin Immunol. 1991 Dec;3(6):924-9. doi: 10.1016/s0952-7915(05)80015-9.

DOI:10.1016/s0952-7915(05)80015-9

PMID:1793537

Abstract

In recent years, studies have suggested that autoimmunity and/or immunopathology may sometimes result from the immune response to heat shock proteins of autologous cells and microorganisms. Focusing on the T-cell mediated responses, we review the latest literature on this issue with regard to three hypothetical concepts of immunopathology in which heat shock proteins might play a role.

摘要

近年来，研究表明自身免疫和/或免疫病理学有时可能源于对自体细胞和微生物热休克蛋白的免疫反应。聚焦于T细胞介导的反应，我们就热休克蛋白可能发挥作用的三种免疫病理学假说概念，回顾了关于这一问题的最新文献。