Adnams Colleen M, Sorour Pharyn, Kalberg Wendy O, Kodituwakku Piyadasa, Perold Mariechen D, Kotze Anna, September Sean, Castle Bernice, Gossage J, May Philip A
Department of Paediatrics, School of Child and Adolescent Health, University of Cape Town, South Africa.
Alcohol. 2007 Sep;41(6):403-14. doi: 10.1016/j.alcohol.2007.07.005.
This pilot study investigated the efficacy of a classroom language and literacy intervention in children with fetal alcohol spectrum disorders (FASD) in the Western Cape Province of South Africa. The study forms part of a larger, ongoing study that includes metacognitive and family support interventions in addition to language and literacy training (LLT). For the LLT study, 65 nine-year-old children identified as either FASD or not prenatally exposed to alcohol, were recruited. Forty children with FASD were randomly assigned to either a LLT intervention group or FASD control group (FASD-C). Twenty-five nonalcohol-exposed children were randomly selected as nonexposed controls (NONEXP-C). Prior to intervention and after nine school-term months of treatment, general scholastic tests, teacher and parent questionnaires, classroom observations and specific language and literacy tests were administered to the participants. The nine months assessment reflects the midpoint and the first assessment stage of the overall study. At initial diagnosis and prior to commencement of the interventions, participants with FASD were significantly weaker than NONEXP-C children in reading, spelling, addition, subtraction, phonological awareness, and other tests of early literacy. Teachers rated a range of adaptive behaviors of children with FASD as significantly worse than NONEXP-C. Mean scholastic and language and literacy scores for all groups showed improvement over baseline scores after 9 months of intervention. The mean test scores of children with FASD remained lower than those of NONEXP-C. Comparison of mean baseline to postintervention score changes between the LLT, FASD-C, and NONEXP-C groups revealed that although there were no significant gains by the LLT intervention group over control groups on the general scholastic assessment battery, significantly greater improvements occurred in the LLT intervention group compared to the FASD-C group in specific categories of language and early literacy. These categories were syllable manipulation, letter sound knowledge, written letters, word reading and nonword reading, and spelling. In spite of cognitive and classroom behavioral difficulties, children with FASD from a vulnerable environment demonstrated significant cognitive improvements in specific areas targeted by classroom interventions. To our knowledge, this is the first report of a systematic classroom intervention and resultant cognitive response in children with FASD.
这项试点研究调查了南非西开普省针对患有胎儿酒精谱系障碍(FASD)儿童的课堂语言和读写能力干预措施的效果。该研究是一项规模更大的正在进行的研究的一部分,除了语言和读写能力培训(LLT)外,还包括元认知和家庭支持干预措施。对于LLT研究,招募了65名9岁儿童,这些儿童被确定为患有FASD或产前未接触过酒精。40名患有FASD的儿童被随机分配到LLT干预组或FASD对照组(FASD-C)。25名未接触酒精的儿童被随机选为未接触对照组(NONEXP-C)。在干预前和经过九个学期月的治疗后,对参与者进行了一般学业测试、教师和家长问卷、课堂观察以及特定的语言和读写能力测试。九个月的评估反映了整个研究的中点和第一个评估阶段。在初步诊断和干预开始前,患有FASD的参与者在阅读、拼写、加法、减法、语音意识以及其他早期读写能力测试方面明显比NONEXP-C儿童弱。教师对患有FASD儿童的一系列适应行为的评分明显低于NONEXP-C儿童。经过9个月的干预,所有组的平均学业成绩以及语言和读写能力得分均比基线得分有所提高。患有FASD儿童的平均测试成绩仍低于NONEXP-C儿童。对LLT组、FASD-C组和NONEXP-C组干预后与基线得分变化的平均值进行比较发现,虽然LLT干预组在一般学业评估电池上与对照组相比没有显著提高,但与FASD-C组相比,LLT干预组在特定的语言和早期读写能力类别上有更大的改善。这些类别包括音节操作、字母发音知识、书写字母、单词阅读和非单词阅读以及拼写。尽管存在认知和课堂行为困难,但来自弱势环境的患有FASD的儿童在课堂干预所针对的特定领域表现出显著的认知改善。据我们所知,这是关于对患有FASD儿童进行系统性课堂干预及其认知反应结果的首份报告。