Suzuki Shunji, Igarashi Miwa
Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, Katsushika-ku, Tokyo, 124-0012, Japan.
Arch Gynecol Obstet. 2008 Apr;277(4):299-301. doi: 10.1007/s00404-007-0482-6. Epub 2007 Oct 16.
This study examined the clinical significance of patients complicated by succenturiate lobes of placenta in comparison with patients with normal placenta.
Data were collected from 47 patients complicated by succenturiate lobes of placenta and from 7,666 unaffected controls.
The frequency of maternal age > or =35 years and history of using in vitro fertilization in patients complicated by succenturiate lobes of placenta were significantly higher than those in control patients (P < 0.01). In addition, the incidence of non-reassuring fetal status, vasa previa, postpartum hemorrhage and retained placenta in the study group were significantly higher than those in control (P < 0.01).
These results support the adverse obstetric outcomes in pregnancies with succenturiate lobes of placenta and may suggest the pathogenesis of these placental shape aberrations associated with assisted reproductive technology.
本研究比较了合并副胎盘叶的患者与胎盘正常患者的临床意义。
收集了47例合并副胎盘叶的患者和7666例未受影响的对照者的数据。
合并副胎盘叶的患者中，产妇年龄≥35岁及使用体外受精的病史发生率显著高于对照患者（P<0.01）。此外，研究组胎儿状况不良、前置血管、产后出血和胎盘残留的发生率显著高于对照组（P<0.01）。
这些结果支持了副胎盘叶妊娠的不良产科结局，并可能提示这些胎盘形态异常与辅助生殖技术相关的发病机制。
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