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在2004 - 2006年BfT - GermVet监测项目中测定的猪、马、犬和猫源大肠杆菌的抗菌药敏性。

Antimicrobial susceptibility of Escherichia coli from swine, horses, dogs and cats as determined in the BfT-GermVet monitoring program 2004-2006.

作者信息

Grobbel Mirjam, Lübke-Becker Antina, Alesík Eva, Schwarz Stefan, Wallmann Jürgen, Werckenthin Christiane, Wieler Lothar H

机构信息

Institut für Mikrobiologie und Tierseuchen, Fachbereich Veterinärmedizin, Freie Universität Berlin.

出版信息

Berl Munch Tierarztl Wochenschr. 2007 Sep-Oct;120(9-10):391-401.

Abstract

A total of 417 isolates of Escherichia coli collected from five animal species/organ system combinations from swine [urinary/genital tract (UGT) incl. mastitis metritis agalactia syndrome], horses [genital tract (GT)] and dogs/cats [respiratory tract (RT), UGT and gastrointestinal tract (GIT)] were analysed quantitatively for their susceptibility against different antimicrobial agents by determination of minimum inhibitory concentrations. Regardless of which animal species the strains originated from, resistance appeared most frequently against sulfamethoxazole (18-59%), tetracycline (14-54 %), and ampicillin (14-39%). High percentages of intermediate isolates were observed for cephalothin (39-46 %). In general, low prevalences of resistance were detected for amoxicillin/clavulanic acid (1-4%), gentamicin (1-9%), and cefazolin (0-11%). Generally speaking, the antimicrobial resistance situation among E. coli isolates from horses and small animals is relatively good.

摘要

对从猪[泌尿/生殖道(UGT),包括无乳症、子宫炎、乳腺炎综合征]、马[生殖道(GT)]以及犬/猫[呼吸道(RT)、泌尿生殖道(UGT)和胃肠道(GIT)]的五种动物物种/器官系统组合中收集的总共417株大肠杆菌分离株,通过测定最低抑菌浓度,对其对不同抗菌药物的敏感性进行了定量分析。无论菌株源自哪种动物物种,对磺胺甲恶唑(18 - 59%)、四环素(14 - 54%)和氨苄西林(14 - 39%)的耐药性出现频率最高。头孢噻吩的中度分离株比例较高(39 - 46%)。一般来说,阿莫西林/克拉维酸(1 - 4%)、庆大霉素(1 - 9%)和头孢唑林(0 - 11%)的耐药率较低。总体而言,马和小型动物的大肠杆菌分离株中的抗菌药物耐药情况相对较好。

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