Smith Cassandra, Bush Jacqueline, Sutija Vesna G
Department of Obstetrics, North Central Bronx Hospital, Bronx, USA.
J Reprod Med. 2007 Sep;52(9):801-4.
To determine whether women with an adverse obstetric history are at greater risk of ectopic pregnancy.
A retrospective, case-control study was conducted on ectopic (case) and intrauterine (control) pregnancies at New York Methodist Hospital between January 2000 and April 2004. There were 67 patients in each group, matched by age and gravidity. Number of pregnancies (G) was stratified by parity (P1-4). Interruption of pregnancy prior to 20 weeks (P3) was further stratified into spontaneous and voluntary abortion and prior ectopic pregnancy.
There were 285 ectopic and 286 control pregnancies. There were more term births (P1: 239 vs. 100) and more live children (P4: 241 vs. 103) in the control group, (p < 0.001), but the number of interrupted pregnancies (P3) was higher (182 vs. 43, p < 0.001) in the ectopic group. The ectopic group had more voluntary (144) and spontaneous interruptions (38) than the control group (18 and 25) (p < 0.001). The ectopic group had more surgeries (57), with 34 dilation and curettages; the control group had 30 surgeries and 11 dilation and curettages (p < 0.001).
Women with an adverse obstetric history that included interrupted pregnancies were more likely to have ectopic pregnancies.
确定有不良产科病史的女性发生异位妊娠的风险是否更高。
对2000年1月至2004年4月在纽约卫理公会医院的异位妊娠（病例组）和宫内妊娠（对照组）进行了一项回顾性病例对照研究。每组有67例患者，按年龄和孕次匹配。妊娠次数（G）按产次（P1 - 4）分层。20周前的妊娠中断（P3）进一步分为自然流产、人工流产和既往异位妊娠。
共有285例异位妊娠和286例对照妊娠。对照组足月分娩（P1：239例对100例）和存活子女（P4：241例对103例）更多（p < 0.001），但异位妊娠组妊娠中断次数（P3）更高（182例对43例，p < 0.001）。异位妊娠组的人工流产（144例）和自然流产（38例）多于对照组（18例和25例）（p < 0.001）。异位妊娠组手术更多（57例），其中刮宫术34例；对照组手术30例，刮宫术11例（p < 0.001）。
有包括妊娠中断在内的不良产科病史的女性更易发生异位妊娠。
