Rikimaru Fumihide, Tomita Kichinobu
Division of Head Neck Surgery, National Hospital Organization Kyushu Cancer Center, Notame, Fukuoka, Japan.
Gan To Kagaku Ryoho. 2007 Oct;34(10):1535-7.
Cisplatin and infusional 5-fluorouracil were most commonly used as neoadjuvant chemotherapy or induction chemotherapy for squamous cell carcinoma of head and neck (SCCHN). But current analysis of neoadjuvant chemotherapy trials in head and neck cancer have not demonstrated a survival benefit for the use of induction therapy. Taxanes are an effective anti-cancer drug for SCCHN. New regimens including Taxanes as neoadjuvant chemotherapy for SCCHN are recommended.
顺铂和静脉输注5-氟尿嘧啶最常用于头颈部鳞状细胞癌（SCCHN）的新辅助化疗或诱导化疗。但目前对头颈部癌新辅助化疗试验的分析并未显示诱导治疗能带来生存获益。紫杉烷类是治疗SCCHN的一种有效抗癌药物。推荐包括紫杉烷类作为SCCHN新辅助化疗的新方案。
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