Sofikerim Mustafa, Demirci Deniz, Huri Emre, Erşekerci Erol, Karacagil Mustafa
Department of Urology, Erciyes University School of Medicine, Kayseri, Turkey.
J Endourol. 2007 Sep;21(9):967-72. doi: 10.1089/end.2006.0216.
This study was designed to determine the outcome and safety of tubeless percutaneous nephrolithotomy (PCNL) in the treatment of renal calculi.
Between November 2005 and March 2006, 48 patients were randomized to either an 18F Re-entry nephrostomy tube (group 1) or a 6F Double-J stent (group 2). The two groups were well matched for age, sex, stone size, stone laterality, and number of previous renal procedures. All PCNL procedures were performed by the same surgeon. Postoperative visual analog pain scale (VAS) scores at 8 and 24 hours and 14 days after surgery, in-hospital analgesic use, length of hospital stay, success rate, blood transfusion rate, and postoperative complications were compared for the two groups.
The mean hospital stays in groups 1 and 2 were 3.1 and 1.6 days, respectively (P = 0.003). The mean VAS scores 8 and 24 hours after surgery were significantly lower in group 2 than in group 1 (P = 0.001). The postoperative analgesic requirement (diclofenac sodium) was significantly higher in group 1 (263 mg) than in group 2 (120 mg; P = 0.02). The rate of blood transfusion in the two groups was similar (P = NS). There was no difference between the groups in VAS scores on postoperative day 14. The number of supracostal accesses was significantly higher in group 2 than in group 1 (P = 0.02). The stone-free rates and the numbers of patients with insignificant residual fragments were similar in the two groups. There was no urine leakage or formation of urinoma in patients with Double-J stents.
Tubeless PCNL is safe and effective even after supracostal access and is associated with less postoperative pain and a shorter hospital stay.
本研究旨在确定无管经皮肾镜取石术(PCNL)治疗肾结石的疗效及安全性。
2005年11月至2006年3月期间,48例患者被随机分为两组,一组置入18F再入路肾造瘘管(第1组),另一组置入6F双J管(第2组)。两组在年龄、性别、结石大小、结石位置及既往肾脏手术次数方面匹配良好。所有PCNL手术均由同一位外科医生完成。比较两组术后8小时、24小时及14天的视觉模拟疼痛量表(VAS)评分、住院期间镇痛药物使用情况、住院时间、成功率、输血率及术后并发症。
第1组和第2组的平均住院时间分别为3.1天和1.6天(P = 0.003)。术后8小时和24小时,第2组的平均VAS评分显著低于第1组(P = 0.001)。第1组术后镇痛药物(双氯芬酸钠)需求量(263 mg)显著高于第2组(120 mg;P = 0.02)。两组输血率相似(P = 无显著性差异)。两组术后14天的VAS评分无差异。第2组肋上入路次数显著高于第1组(P = 0.02)。两组结石清除率及残留碎片不明显的患者数量相似。置入双J管的患者未出现尿液漏出或尿瘤形成。
即使采用肋上入路,无管PCNL也是安全有效的,且术后疼痛较轻,住院时间较短。