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完全无管化与标准经皮肾镜取石术治疗肾结石:临床结果与成本分析

Totally tubeless versus standard percutaneous nephrolithotomy for renal stones: analysis of clinical outcomes and cost.

作者信息

Choi Sae Woong, Kim Kang Sup, Kim Jeong Ho, Park Yong Hyun, Bae Woong Jin, Hong Sung-Hoo, Lee Ji Youl, Kim Sae Woong, Hwang Tae-Kon, Cho Hyuk Jin

机构信息

Department of Urology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea , Seoul, Republic of Korea.

出版信息

J Endourol. 2014 Dec;28(12):1487-94. doi: 10.1089/end.2014.0421.

Abstract

PURPOSE

To evaluate the safety and cost-effectiveness of a totally tubeless percutaneous nephrolithotomy (PCNL) by comparing the clinical outcomes and cost analysis between standard PCNL and totally tubeless PCNL for renal stones.

PATIENTS AND METHODS

From June 2012 to September 2013, a total of 121 patients with renal stones who underwent totally tubeless or standard PCNL by two experienced surgeons were retrospectively evaluated by group. According to the surgeon's preference for the nephrostomy tube and/or ureteral stent, the present study was designed to be divided into Group 1 and Group 2. Group 1 was performed by one surgeon (H.J. Cho) who preferred a totally tubeless PCNL and Group 2 was performed by the other surgeon (S.H. Hong) who preferred a standard PCNL. We excluded bilateral renal stones, multiple approach, whole staghorn calculi, and previous renal surgery. Patient and stone characteristics, intraoperative and postoperative parameters, and cost analysis were compared between the two groups.

RESULTS

There were no significant differences in the patient demographics between groups. Mean stone burden was 501.5±361.1 mm(2) in Group 1 v 535.2±353.1 mm(2) in Group 2 (P=0.651). Length of hospital stay (1.72±0.58 v 4.10±1.88 days, P<0.001), postoperative pain scores using a visual analog scale (day 0: P<0.001, day 1: P=0.002), and analgesia requirements (33.2±21.3 v 45.2±19.5 mg, P=0.005) for Group 1 v Group 2 showed significant differences. The stone-free rate was 86.4% v 89.8% in Group 1 and Group 2, respectively (P=0.609). There were no significant differences in overall complications between groups (P=0.213). Mean total medical treatment costs in Groups 1 and 2 were 2398.22±549.1 USD and 2845.70±824.2 USD, respectively (P=0.002).

CONCLUSIONS

Many clinical outcomes in the totally tubeless PCNL showed comparable or better results than standard PCNL. We believe that totally tubeless PCNL is an acceptable, safe, and cost-effective alternative to standard PCNL for the treatment of renal stones.

摘要

目的

通过比较标准经皮肾镜取石术(PCNL)和完全无管PCNL治疗肾结石的临床结果及成本分析,评估完全无管PCNL的安全性和成本效益。

患者与方法

回顾性分析2012年6月至2013年9月期间,由两位经验丰富的外科医生对121例接受完全无管或标准PCNL治疗的肾结石患者进行分组评估。根据外科医生对肾造瘘管和/或输尿管支架的偏好,本研究设计分为第1组和第2组。第1组由一位倾向于完全无管PCNL的外科医生(赵贤珠)实施手术,第2组由另一位倾向于标准PCNL的外科医生(洪圣勋)实施手术。我们排除了双侧肾结石、多通道手术、完全鹿角形结石以及既往肾脏手术患者。比较两组患者及结石特征、术中及术后参数和成本分析。

结果

两组患者人口统计学特征无显著差异。第1组平均结石负荷为501.5±361.1 mm(2),第2组为535.2±353.1 mm(2)(P = 0.651)。第1组与第2组相比,住院时间(1.72±0.58对4.10±1.88天,P<0.001)、采用视觉模拟量表的术后疼痛评分(第0天:P<0.001,第1天:P = 0.002)以及镇痛需求(33.2±21.3对45.2±19.5 mg,P = 0.005)存在显著差异。第1组和第2组的结石清除率分别为86.4%和89.8%(P = 0.609)。两组总体并发症无显著差异(P = 0.213)。第1组和第2组的平均总医疗费用分别为2398.22±549.1美元和2845.70±824.2美元(P = 0.002)。

结论

完全无管PCNL的许多临床结果显示与标准PCNL相当或更好。我们认为,完全无管PCNL是治疗肾结石的一种可接受、安全且具有成本效益的替代标准PCNL的方法。

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