Quiton Raimi L, Greenspan Joel D
Department of Biomedical Sciences, Dental School, and Program in Neuroscience, University of Maryland, Baltimore, MD, USA.
Pain. 2008 Jul 15;137(2):245-256. doi: 10.1016/j.pain.2007.08.034. Epub 2007 Oct 17.
This study examined within- and across-session consistency of visual analog scale (VAS) pain intensity and unpleasantness ratings of contact heat stimuli in 64 subjects (32 male). Subjects participated in four sessions over 14 days, with three stimulus series per session. Two levels of painful heat (pain-lo: rated 40, and pain-hi: rated 70 on a 0-100 VAS) were delivered in randomized order during each series, with temperatures selected on an individual subject basis to equalize pain perception across subjects. Across-session ratings declined by the fourth session for both pain levels (p=0.01). Within-session ratings declined by the third series for both pain levels (p<0.001). While significant, changes in across- and within-session ratings were of small magnitude. Comparison of coefficients of variation (CVs) for across- and within-session ratings revealed that pain-lo ratings were more variable than pain-hi ratings (p<0.001). Across- and within-session CVs were highly correlated for each pain level (pain-lo p<0.001; pain-hi p=0.001), suggesting that variability of VAS ratings is a characteristic of individual subjects over both short and long time scales. Across- and within-session CVs were significantly negatively correlated with individual ratings of the stimuli, but were not correlated with demographic or psychosocial factors. Furthermore, sex did not impact consistency of ratings, demonstrating that neither sex is more variable in ratings than the other over time. Taken together, these findings suggest that VAS ratings of painful contact heat are relatively stable over time but the variability of these ratings is significantly impacted by the perceived intensity of the stimulus.
本研究调查了64名受试者(32名男性)视觉模拟量表(VAS)对接触热刺激的疼痛强度和不愉快程度评分在不同时段内及不同时段间的一致性。受试者在14天内参加了四个时段的实验,每个时段有三个刺激系列。在每个系列中,以随机顺序施加两种疼痛热水平(低疼痛水平:在0 - 100的VAS上评为40,高疼痛水平:评为70),根据个体受试者情况选择温度,以使受试者间的疼痛感知相等。两种疼痛水平在第四个时段时不同时段间的评分均下降(p = 0.01)。两种疼痛水平在第三个刺激系列时不同时段内的评分均下降(p < 0.001)。虽然有显著变化,但不同时段间和不同时段内评分的变化幅度较小。对不同时段间和不同时段内评分的变异系数(CV)进行比较发现,低疼痛水平评分比高疼痛水平评分更具变异性(p < 0.001)。每个疼痛水平的不同时段间和不同时段内CV高度相关(低疼痛水平p < 0.001;高疼痛水平p = 0.001),这表明VAS评分的变异性是个体受试者在短期和长期时间尺度上的一个特征。不同时段间和不同时段内的CV与对刺激的个体评分显著负相关,但与人口统计学或心理社会因素无关。此外,性别不影响评分的一致性,这表明随着时间推移,两种性别在评分变异性方面并无差异。综上所述,这些发现表明,疼痛接触热的VAS评分随时间相对稳定,但这些评分的变异性受到刺激感知强度的显著影响。