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滇西马先蒿的抗菌成分。

Antibacterial constituents from Pedicularis armata.

作者信息

Yuan Cheng-Shan, Sun Xiao-Bai, Zhao Pei-Hua, Cao Mei-Ai

机构信息

State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, China.

出版信息

J Asian Nat Prod Res. 2007 Sep-Dec;9(6-8):673-7. doi: 10.1080/10286020601103171.

Abstract

A new neolignan glycoside named armaoside (1), together with six known compounds (2-7), have been isolated from the whole plant of Pedicularis armata Maxim. The structure of 1 was elucidated as erythro-(7S,8R)-1-(4-O-beta-D-glucopyranosyl-3-methoxyphenyl)-2-[3,5-dimethoxyl-4-oxo-cinnamic aldehyde]propane-1, 3-diol by spectroscopic and chemical methods. All compounds were assayed against Bacillus subtilis, Escherichia coli, and Staphylococcus aureus.

摘要

从长花马先蒿(Pedicularis armata Maxim)全草中分离得到了一种名为马先蒿苷(1)的新木脂素糖苷以及六种已知化合物(2 - 7)。通过光谱和化学方法确定1的结构为赤式-(7S,8R)-1-(4 - O-β-D-吡喃葡萄糖基-3-甲氧基苯基)-2-[3,5-二甲氧基-4-氧代肉桂醛]丙烷-1,3-二醇。对所有化合物进行了针对枯草芽孢杆菌、大肠杆菌和金黄色葡萄球菌的活性测试。

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