Thompson Alex, Fan Ming-Yu, Unützer Jürgen, Katon Wayne
University of Washington School of Medicine, Department of Psychiatry and Behavioral Sciences, Seattle, WA 98195-6560, USA.
Int J Geriatr Psychiatry. 2008 May;23(5):511-6. doi: 10.1002/gps.1929.
Depression occurs in 5-10% of older adults and there are nearly 6 million informal caregivers aged 65 or older. Prior research has focused on vulnerability to psychological distress in caregivers. Research has not addressed the caregiving burden of depressed elderly patients or how that burden affects depression treatment outcomes.
To describe the self-reported caregiving burden in a large, representative cohort of depressed elderly patients and compare depression treatment outcomes between caregivers and non-caregivers.
Univariate and multiple regression analyses were performed comparing 24-month depression outcomes (measured as depression free days) in those providing care at any time over the 24-month trial to those who never reported a caregiving burden.
At 3, 6, 12, 18, and 24 months, nearly 10% of cohabitating elderly depressed patients provided care for basic activities such as bathing or dressing while nearly 20% reported providing care for other activities such as making phone calls or taking medication. Over 24 months, after adjusting for marital status, intervention status, and number of medical comorbidities, those reporting any caregiving burden had over 30 more days with depression compared to those with no caregiving burden. The IMPACT collaborative care model did not modify the effect of caregiving on depression outcomes.
Caregiving is common in depressed older adults and appears to affect response to depression treatment. In the future, interventions for depressed older adults should consider and specifically address caregiving activities in addition to specific depression treatment.
5%至10%的老年人患有抑郁症,且有近600万年龄在65岁及以上的非正式照料者。先前的研究聚焦于照料者心理困扰的易感性。研究尚未涉及老年抑郁症患者的照料负担,以及该负担如何影响抑郁症治疗效果。
描述大量具有代表性的老年抑郁症患者队列中自我报告的照料负担,并比较照料者与非照料者之间的抑郁症治疗效果。
进行单因素和多因素回归分析,比较在24个月试验期间任何时间提供照料的患者与从未报告有照料负担的患者的24个月抑郁症结局(以无抑郁天数衡量)。
在3个月、6个月、12个月、18个月和24个月时,近10%的同居老年抑郁症患者为诸如洗澡或穿衣等基本活动提供照料,而近20%的患者报告为诸如打电话或服药等其他活动提供照料。在24个月期间,在调整婚姻状况、干预状态和合并症数量后,报告有任何照料负担的患者比没有照料负担的患者患抑郁症的天数多30多天。IMPACT协作护理模式并未改变照料对抑郁症结局的影响。
照料在老年抑郁症患者中很常见,且似乎会影响抑郁症治疗反应。未来,针对老年抑郁症患者的干预措施除了特定的抑郁症治疗外,还应考虑并具体解决照料活动问题。