Park Mijung, Unützer Jürgen
University of Pittsburgh School of Nursing, Department of Health and Community Systems, Pittsburgh, PA, USA.
Int J Geriatr Psychiatry. 2014 Dec;29(12):1271-7. doi: 10.1002/gps.4107. Epub 2014 Apr 4.
Although collaborative care programs are effective in improving late-life depression, only about half of treated patients achieve clinically meaningful improvement. Thus, we need to examine what characteristics may predict poor late-life depression course. Despite the robust evidence for the negative association between the quality of couple relationships and depression outcomes, few studies have examined these associations in the context of long-term late-life depression course.
The objective of this study is to examine the relations between the severity of couple conflict, receiving collaborative depression care program, and 24-months depression outcomes.
Study sample comprised 840 depressed older adults subsample from the improving mood, promoting access to collaborative treatment for late-life depression trial (IMPACT). Depression and couple conflict were assessed at baseline, 12-month, and 24-month follow-up. Descriptive statistics and multivariate regression analyses were performed to examine mean 24-month depression-free days (DFD) and the marginal effects of receiving IMAPCT program over usual care among participants with varying degrees of 24-month couple conflict.
Compared with those who never endorsed frequent couple conflict over the three observation points, those who did twice had 63 fewer DFD (p = 0.01), and those who did three times experienced 148 fewer DFD (p < 0.001). Although the marginal effects of receiving IMPACT program over usual care was greater in overall sample, it was not statistically significant among those who endorsed frequent conflict at two or three times.
Frequent couple conflict is associated with worse long-term late-life depression outcomes among the patients in primary care clinics.
尽管协作护理项目在改善老年抑郁症方面有效,但只有约一半接受治疗的患者实现了具有临床意义的改善。因此,我们需要研究哪些特征可能预示着老年抑郁症病程不佳。尽管有充分证据表明夫妻关系质量与抑郁结局之间存在负相关,但很少有研究在长期老年抑郁症病程的背景下考察这些关联。
本研究的目的是考察夫妻冲突严重程度、接受协作性抑郁症护理项目与24个月抑郁结局之间的关系。
研究样本包括从改善情绪、促进获得老年抑郁症协作治疗试验(IMPACT)中抽取的840名老年抑郁症患者子样本。在基线、12个月和24个月随访时评估抑郁和夫妻冲突情况。进行描述性统计和多变量回归分析,以考察平均24个月无抑郁天数(DFD)以及在不同程度的24个月夫妻冲突的参与者中接受IMPACT项目相对于常规护理的边际效应。
与在三个观察点都从未认可频繁夫妻冲突的人相比,认可两次频繁夫妻冲突的人DFD少63天(p = 0.01),认可三次频繁夫妻冲突的人DFD少148天(p < 0.001)。尽管在总体样本中接受IMPACT项目相对于常规护理的边际效应更大,但在认可两次或三次频繁冲突的人群中无统计学意义。
在初级保健诊所的患者中,频繁的夫妻冲突与更差的长期老年抑郁症结局相关。