Zetterström Charlotta, Kugelberg Maria
Eye Department, Ullevål University Hospital, University of Oslo, Oslo, Norway.
Acta Ophthalmol Scand. 2007 Nov;85(7):698-710. doi: 10.1111/j.1600-0420.2007.01007.x.
Bilateral congenital cataract is the most common cause of treatable childhood blindness. Nuclear cataract is usually present at birth and is non-progressive, while lamellar cataract usually develops later and is progressive. Prompt surgery has to be performed in cases with dense congenital cataract: if nystagmus has developed, the amblyopia is unfortunately irreversible. A treatment regime based on surgery within 2 months of life, combined with prompt optical correction of the aphakia and occlusion therapy with frequent follow-up, have been successful in both unilateral and bilateral cases. The surgery ought to include anterior and posterior capsulorexis in all children at the present time. Intraocular lens implantation has been safely performed below the age of 1 year and has also been successfully performed in bilateral cases. Anterior dry vitrectomy should be performed in preschool children to avoid visual axis opacification. Visual axis opacification is the most common complication found after cataract surgery in children. Secondary glaucoma is by far the most sight-threatening complication and is, unfortunately, common in the newborn so lifelong follow-up is essential in these cases.
双侧先天性白内障是儿童可治疗性失明的最常见原因。核性白内障通常在出生时就存在且不进展,而板层白内障通常较晚出现且会进展。对于致密性先天性白内障病例必须尽早进行手术:如果已经出现眼球震颤,遗憾的是弱视将不可逆转。基于出生后2个月内进行手术、及时对无晶状体眼进行光学矫正以及频繁随访的遮盖疗法的治疗方案,在单侧和双侧病例中均取得了成功。目前所有儿童的手术都应包括前囊和后囊撕开术。1岁以下儿童已安全地进行了人工晶状体植入,双侧病例也已成功实施。对于学龄前儿童应进行前部干性玻璃体切除术以避免视轴混浊。视轴混浊是儿童白内障手术后最常见的并发症。继发性青光眼是迄今为止最具视力威胁的并发症,不幸的是在新生儿中很常见,因此这些病例必须进行终身随访。