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在一家儿科日间治疗中心对使用肠胃外抗生素治疗中度至重度蜂窝织炎的管理进行前瞻性评估。

Prospective evaluation of the management of moderate to severe cellulitis with parenteral antibiotics at a paediatric day treatment centre.

作者信息

Gouin Serge, Chevalier Isabelle, Gauthier Marie, Lamarre Valérie

机构信息

Division of Emergency Medicine, Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.

出版信息

J Paediatr Child Health. 2008 Apr;44(4):214-8. doi: 10.1111/j.1440-1754.2007.01236.x. Epub 2007 Oct 18.

Abstract

AIM

To assess the clinical outcome of patients with moderate to severe cellulitis managed at a paediatric day treatment centre (DTC).

METHODS

Prospective observational study of all patients (3 months to 18 years) with a presumed diagnosis of moderate to severe cellulitis made in a university-affiliated paediatric emergency department (ED) (September 2003 to September 2005). Patients treated at the DTC were given ceftriaxone or clindamycin.

RESULTS

During the study period, a presumed diagnosis of moderate to severe cellulitis was made in 224 patients in the ED. Ninety-two patients were treated at the DTC (41%). The cellulitis had a median width of 7.0 cm (range: 1.0-50.0 cm) and a median length of 6.5 cm (range: 1.0-40.0 cm). Blood cultures were performed in 95.7%; one was positive for Staphylococcus aureus. After a mean of 2.5 days of intravenous therapy (first injection in the ED and a mean of 1.5 days at the DTC), 73 patients (79.3%) were successfully discharged from the DTC and switched to an oral agent. For these patients no relapse occurred. Nineteen patients (20.7%) required inpatient admission for further therapy. No patient was diagnosed with necrotizing fasciitis in the course of therapy. Seventy-eight satisfaction questionnaires were handed in and revealed very good to excellent parental satisfaction with treatment at the DTC in 94.8%.

CONCLUSION

Treatment with parenteral antibiotic at a DTC is a viable alternative to hospitalisation for moderate to severe cellulitis in children.

摘要

目的

评估在儿科日间治疗中心(DTC)接受治疗的中重度蜂窝织炎患者的临床结局。

方法

对一所大学附属医院儿科急诊科(2003年9月至2005年9月)所有疑似诊断为中重度蜂窝织炎的患者(3个月至18岁)进行前瞻性观察研究。在DTC接受治疗的患者给予头孢曲松或克林霉素。

结果

在研究期间,急诊科有224例患者被疑似诊断为中重度蜂窝织炎。92例患者在DTC接受治疗(41%)。蜂窝织炎的中位宽度为7.0厘米(范围:1.0 - 50.0厘米),中位长度为6.5厘米(范围:1.0 - 40.0厘米)。95.7%的患者进行了血培养;1例金黄色葡萄球菌阳性。经过平均2.5天的静脉治疗(在急诊科首次注射,在DTC平均治疗1.5天),73例患者(79.3%)成功从DTC出院并转为口服药物治疗。这些患者未出现复发。19例患者(20.7%)需要住院进一步治疗。治疗过程中没有患者被诊断为坏死性筋膜炎。共提交了78份满意度调查问卷,结果显示94.8%的家长对在DTC的治疗非常满意或极其满意。

结论

对于儿童中重度蜂窝织炎,在DTC进行肠外抗生素治疗是一种可行的替代住院治疗的方法。

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