Gouin Serge, Chevalier Isabelle, Gauthier Marie, Lamarre Valérie
Division of Emergency Medicine, Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.
J Paediatr Child Health. 2008 Apr;44(4):214-8. doi: 10.1111/j.1440-1754.2007.01236.x. Epub 2007 Oct 18.
To assess the clinical outcome of patients with moderate to severe cellulitis managed at a paediatric day treatment centre (DTC).
Prospective observational study of all patients (3 months to 18 years) with a presumed diagnosis of moderate to severe cellulitis made in a university-affiliated paediatric emergency department (ED) (September 2003 to September 2005). Patients treated at the DTC were given ceftriaxone or clindamycin.
During the study period, a presumed diagnosis of moderate to severe cellulitis was made in 224 patients in the ED. Ninety-two patients were treated at the DTC (41%). The cellulitis had a median width of 7.0 cm (range: 1.0-50.0 cm) and a median length of 6.5 cm (range: 1.0-40.0 cm). Blood cultures were performed in 95.7%; one was positive for Staphylococcus aureus. After a mean of 2.5 days of intravenous therapy (first injection in the ED and a mean of 1.5 days at the DTC), 73 patients (79.3%) were successfully discharged from the DTC and switched to an oral agent. For these patients no relapse occurred. Nineteen patients (20.7%) required inpatient admission for further therapy. No patient was diagnosed with necrotizing fasciitis in the course of therapy. Seventy-eight satisfaction questionnaires were handed in and revealed very good to excellent parental satisfaction with treatment at the DTC in 94.8%.
Treatment with parenteral antibiotic at a DTC is a viable alternative to hospitalisation for moderate to severe cellulitis in children.
评估在儿科日间治疗中心(DTC)接受治疗的中重度蜂窝织炎患者的临床结局。
对一所大学附属医院儿科急诊科(2003年9月至2005年9月)所有疑似诊断为中重度蜂窝织炎的患者(3个月至18岁)进行前瞻性观察研究。在DTC接受治疗的患者给予头孢曲松或克林霉素。
在研究期间,急诊科有224例患者被疑似诊断为中重度蜂窝织炎。92例患者在DTC接受治疗(41%)。蜂窝织炎的中位宽度为7.0厘米(范围:1.0 - 50.0厘米),中位长度为6.5厘米(范围:1.0 - 40.0厘米)。95.7%的患者进行了血培养;1例金黄色葡萄球菌阳性。经过平均2.5天的静脉治疗(在急诊科首次注射,在DTC平均治疗1.5天),73例患者(79.3%)成功从DTC出院并转为口服药物治疗。这些患者未出现复发。19例患者(20.7%)需要住院进一步治疗。治疗过程中没有患者被诊断为坏死性筋膜炎。共提交了78份满意度调查问卷,结果显示94.8%的家长对在DTC的治疗非常满意或极其满意。
对于儿童中重度蜂窝织炎,在DTC进行肠外抗生素治疗是一种可行的替代住院治疗的方法。