Kumar D, Carvalho P, Antunes M, Henriques J, Eugenio L, Schmidt R, Habetha J
Centre for Informatics and Systems, University of Coimbra, Portugal.
Conf Proc IEEE Eng Med Biol Soc. 2006;2006:1410-6. doi: 10.1109/IEMBS.2006.260735.
A new unsupervised and low complexity method for detection of S1 and S2 components of heart sound without the ECG reference is described The most reliable and invariant feature applied in current state-of-the-art of unsupervised heart sound segmentation algorithms is implicitly or explicitly the S1-S2 interval regularity. However; this criterion is inherently prone to noise influence and does not appropriately tackle the heart sound segmentation of arrhythmic cases. A solution based upon a high frequency marker; which is extracted from heart sound using the fast wavelet decomposition, is proposed in order to estimate instantaneous heart rate. This marker is physiologically motivated by the accentuated pressure differences found across heart valves, both in native and prosthetic valves, which leads to distinct high frequency signatures of the valve closing sounds. The algorithm has been validated with heart sound samples collected from patients with mechanical and bio prosthetic heart valve implants in different locations, as well as with patients with native valves. This approach exhibits high sensitivity and specificity without being dependent on the valve type nor their implant position. Further more, it exhibits invariance with respect to normal sinus rhythm (NSR) arrhythmias and sound recording location.
本文描述了一种无需心电图参考即可检测心音S1和S2成分的新型无监督且低复杂度方法。在当前最先进的无监督心音分割算法中应用的最可靠且不变的特征,无论是隐含还是明确地,都是S1 - S2间期规律性。然而,该标准本质上容易受到噪声影响,并且不能适当地处理心律失常病例的心音分割。为了估计瞬时心率,提出了一种基于高频标记的解决方案,该标记使用快速小波分解从心音中提取。这种标记在生理上是由在天然瓣膜和人工瓣膜中的心瓣膜上发现的明显压力差所驱动的,这导致了瓣膜关闭声音的独特高频特征。该算法已通过从不同位置植入机械和生物人工心脏瓣膜的患者以及天然瓣膜患者收集的心音样本进行了验证。这种方法具有高灵敏度和特异性,不依赖于瓣膜类型及其植入位置。此外,它对于正常窦性心律(NSR)心律失常和声音记录位置具有不变性。