Polasek Katharine H, Hoyen Harry A, Keith Michael W, Kirsch Robert F, Tyler Dustin J
Dept. of Biomed. Eng., Case Western Reserve Univ., Cleveland, OH, USA.
Conf Proc IEEE Eng Med Biol Soc. 2006;2006:3584-7. doi: 10.1109/IEMBS.2006.259625.
Four nerve cuff electrodes were implanted in the shoulder and arm of one subject with high tetraplegia. Stimulation produced shoulder abduction, elbow flexion and extension, and wrist and finger extension. Recruitment properties were quantified using twitch EMG recruitment curves and tetanic moment measurements. The chronic qualitative 'function' of each channel of stimulation could be predicted from the intraoperative data collection. The average threshold was 11.3 +/- 9 nC and stabilized to this value over the 35 weeks of testing. The moment production of most muscles increased over the testing period due to exercise of the atrophied muscles. No muscle decreased its moment and most appeared to plateau after 15 weeks. Sensation was also evaluated since this subject had an incomplete injury and nerve stimulation was not found to painful throughout the range of muscle activation. Nerve electrodes have been shown to be a stable, effective means of activating muscles for neuroprosthetics.
在一名高位四肢瘫痪患者的肩部和手臂植入了四个神经袖套电极。刺激可产生肩部外展、肘部屈伸以及腕部和手指伸展。通过单收缩肌电图募集曲线和强直力矩测量对募集特性进行量化。每个刺激通道的慢性定性“功能”可根据术中数据收集进行预测。平均阈值为11.3±9纳库仑，并在35周的测试期内稳定在该值。由于萎缩肌肉的锻炼，大多数肌肉的力矩产生在测试期间有所增加。没有肌肉的力矩下降，并且大多数肌肉在15周后似乎达到平稳状态。由于该患者为不完全损伤且在肌肉激活范围内未发现神经刺激有疼痛感，因此也对感觉进行了评估。神经电极已被证明是用于神经假体激活肌肉的一种稳定、有效的手段。
