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锌对镉引起的脂质过氧化的保护作用。

Zinc protection against lipid peroxidation from cadmium.

作者信息

Khan S, Khan M A, Bhatnagar D, Yadav P, Sarkar S

机构信息

School of Biochemistry, D.A. University, Indore, India.

出版信息

Indian J Exp Biol. 1991 Sep;29(9):823-5.

PMID:1794864
Abstract

Effect of zinc and cadmium on lipid peroxidation and catalase activity in liver, heart, brain and testis was determined in order to characterise the interaction of zinc with cadmium. Zinc and cadmium both increased lipid peroxidation significantly in the tissues studied. In animals pretreated with zinc prior to cadmium administration, significant decrease in lipid peroxidation in liver was observed. Lipid peroxidation was not affected significantly in testis but a significant increase was observed in heart and brain tissues. Catalase activity in testis increased significantly by zinc treatment with or without cadmium administration.

摘要

为了表征锌与镉的相互作用,测定了锌和镉对肝脏、心脏、大脑和睾丸中脂质过氧化和过氧化氢酶活性的影响。锌和镉均显著增加了所研究组织中的脂质过氧化。在镉给药前用锌预处理的动物中,观察到肝脏中脂质过氧化显著降低。睾丸中的脂质过氧化没有受到显著影响,但在心脏和脑组织中观察到显著增加。无论是否给予镉,锌处理均使睾丸中的过氧化氢酶活性显著增加。

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