Zaragozá García José Miguel, Plaza Martínez Angel, Briones Estébanez Johissy Lissethe, Martínez Parreño Carlos, Gómez Palonés Francisco Julián, Ortiz Monzón Eduardo
Servicio de Angiología, Cirugía Vascular y Endovascular, Hospital Universitario Dr. Peset. Valencia, España.
Med Clin (Barc). 2007 Oct 6;129(12):451-3. doi: 10.1157/13111003.
The aim of this study was to investigate the accuracy of color Doppler-ultrasonography (CDU) compared with biopsy for the diagnosis of temporal arteritis (TA).
Twenty-three patients with suspected TA on the basis of clinical criteria were evaluated with CDU prior to temporal artery biopsy. The presence of a hypoechoic halo, suggesting edema of the inflamed vessel, and inflammatory stenoses were registered. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and eficiency or global test value (GTV) were evaluated.
All patients completed a bilateral CDU examination of temporal arteries, and in 72% of patients the biopsy was negative for TA. When the presence of an halo in CDU examination was regarded as determinant for disease, sensitivity, specificity, PPV, NPV and GTV compared with TA histologic confirmation were 80%, 92%, 80%, 92% and 88%, respectively. When the criteria used was presence of the halo sign with or without inflammatory stenosis, the values were 100%, 77%, 62.5%, 100% and 83% respectively.
Because of the high sensitivity and NPV, we consider CDU as a good screening test for the diagnosis of TA.
本研究旨在探讨彩色多普勒超声（CDU）与活检相比在颞动脉炎（TA）诊断中的准确性。
对23例基于临床标准疑似患有TA的患者在进行颞动脉活检前采用CDU进行评估。记录有无提示炎症血管水肿的低回声晕以及炎性狭窄情况。评估敏感性、特异性、阳性预测值（PPV）、阴性预测值（NPV）和效能或总体检验值（GTV）。
所有患者均完成了双侧颞动脉的CDU检查，72%的患者活检结果显示TA为阴性。当将CDU检查中出现晕视为疾病的决定因素时，与TA组织学确诊相比，敏感性、特异性、PPV、NPV和GTV分别为80%、92%、80%、92%和88%。当使用的标准是有无晕征及有无炎性狭窄时，相应的值分别为100%、77%、62.5%、100%和83%。
由于高敏感性和NPV，我们认为CDU是TA诊断的一种良好筛查方法。
