Adachi Naoto, Adachi Takuya, Akanuma Nozomi, Matsubara Ryouji, Ito Masumi, Takekawa Yoshikazu, Ikeda Hiroshi, Arai Heii
Adachi Mental Clinic, Sapporo 004-0867, Japan.
Compr Psychiatry. 2007 Nov-Dec;48(6):592-6. doi: 10.1016/j.comppsych.2007.05.014. Epub 2007 Aug 20.
To clarify why patients with schizophrenia show déjà vu experiences less frequently, we studied déjà vu experiences in 113 schizophrenic patients in relation to psychopathologies and antipsychotic medication. Déjà vu experiences were observed in 53.1% of the schizophrenic patients. Patients with increased negative symptoms (blunted affect, motor retardation, emotional withdrawal, conceptual disorganization, and mannerisms) had déjà vu experiences less frequently. The other psychopathologies were not significantly associated with presence of déjà vu experiences. The dosage of antipsychotic drugs was significantly correlated with the frequency of déjà vu experiences. This correlation was not affected by their psychopathologies at the time of examination. The decreased frequency of déjà vu experiences in patients with schizophrenia may be mainly due to the negative symptoms. The positive relation between frequency of déjà vu experiences and the dosage of neuroleptics remains uncertain.
为阐明精神分裂症患者幻觉重现体验较少出现的原因，我们研究了113例精神分裂症患者的幻觉重现体验与精神病理学及抗精神病药物治疗的关系。53.1%的精神分裂症患者出现过幻觉重现体验。阴性症状（情感迟钝、运动迟缓、情感退缩、概念紊乱及怪癖行为）加重的患者幻觉重现体验较少。其他精神病理学表现与幻觉重现体验的存在无显著关联。抗精神病药物的剂量与幻觉重现体验的频率显著相关。这种相关性不受检查时其精神病理学表现的影响。精神分裂症患者幻觉重现体验频率降低可能主要归因于阴性症状。幻觉重现体验频率与抗精神病药物剂量之间的正相关关系仍不确定。
