Leontiev Oleg, Dubinsky Theodore J
School of Medicine, University of California, San Diego, UCSD Center for Functional MRI, 9500 Gilman Dr., Mail Code 0677, La Jolla, CA 92093-0677, USA.
AJR Am J Roentgenol. 2007 Nov;189(5):1061-3. doi: 10.2214/AJR.07.2591.
The purpose of this article is to examine the value of coronary artery calcium scoring as a screening tool for identifying individuals at risk of experiencing a catastrophic coronary event.
Because of the noninvasive nature of CT and the large societal burden of coronary atherosclerosis, there is great interest in developing CT-based techniques for detection of coronary artery calcium, a known marker of underlying atherosclerosis. However, important questions remain including the role of calcium in the process of acute plaque rupture, the utility of this technique in the asymptomatic population, and the statistical distribution of calcium scores and hard cardiac events in the general population.
本文旨在探讨冠状动脉钙化评分作为一种筛查工具，用于识别有发生灾难性冠状动脉事件风险个体的价值。
由于CT的无创性以及冠状动脉粥样硬化带来的巨大社会负担，人们对开发基于CT的技术来检测冠状动脉钙化（一种已知的潜在动脉粥样硬化标志物）有着浓厚兴趣。然而，重要问题依然存在，包括钙在急性斑块破裂过程中的作用、该技术在无症状人群中的效用，以及一般人群中钙化评分和严重心脏事件的统计分布情况。
