Britov A N, Kobal' A M, Orlov S N, Pokudin N I, Sapozhnikov I I, Grishenkov E A
Kardiologiia. 1991 Aug;31(8):54-8.
The relation of red blood cell Na+/Li+ countertransport rate to the prevalence of arterial hypertension (AH) and blood pressure was evaluated in 720 individuals aged 23-60 years. In all age groups, the rate of red blood cell Na+/Li+ countertransport was significantly higher in males than in females. Age, alcohol use, obesity in males and age, obesity, and Na+/Li+ countertransport rate in females are factors that predispose to AH, as evidenced by multivariate logistic analysis. The latter parameter is associated with obesity and diastolic blood pressure and unassociated with age, alcohol use, and smoke, as suggested by regression analysis. The distribution of Na+/Li+ countertransport rate values in the population after standardization for ruling out the impact of obesity is erroneous and shifted to the right. This allows it to be presented as a sum of two normal distributions. However, their analysis has failed to reveal statistically significant differences in blood pressure values of AH incidence. The rate of Na+/Li+ countertransport may be regarded as a biological population risk factor for AH, which is, however, less than such factors as age, obesity, and excessive alcohol use.
在720名年龄在23至60岁的个体中，评估了红细胞钠/锂逆向转运速率与动脉高血压（AH）患病率及血压之间的关系。在所有年龄组中，男性红细胞钠/锂逆向转运速率显著高于女性。多因素逻辑分析表明，年龄、饮酒、男性肥胖以及年龄、肥胖和女性钠/锂逆向转运速率是易患AH的因素。回归分析表明，后一参数与肥胖和舒张压相关，与年龄、饮酒和吸烟无关。排除肥胖影响后，人群中钠/锂逆向转运速率值的分布是错误的且向右偏移。这使得它可以表示为两个正态分布的总和。然而，对其分析未能揭示AH发病率血压值的统计学显著差异。钠/锂逆向转运速率可被视为AH的生物群体风险因素，不过，它比年龄、肥胖和过度饮酒等因素的风险要小。
