Zaheer S A, Suresh N R, Kar H K, Sharma A K, Mukherjee A, Mukherjee R, Talwar G P
National Institute of Immunology, New Delhi, India.
Lepr Rev. 1991 Sep;62(3):297-302. doi: 10.5935/0305-7518.19910036.
Immunotherapy with Mycobacterium w was given, in addition to standard multidrug therapy (MDT) to a lepromatous leprosy (LL) patient with a bacteriological index (BI) of 6. After 15 months of treatment this patient attained bacteriological negativity and clinical inactivity. Histopathologically the patient upgraded to borderline-tuberculoid at 12 months, and at 15 months showed features of nonspecific infiltration in the dermis. The rapid immunological upgrading seen in the patient is highlighted in this paper.
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