Gitsu G A, Nguyen T Kh, Ballad N E, Kha V V, Kieu T L, Ivashchenko E A
Med Parazitol (Mosk). 1991 Jul-Aug(4):20-3.
An enzyme immunoassay with homologous and heterologous antigens has been elaborated for the diagnosis of clonorchiasis. 251 blood serum samples from patients with clonorchiasis have been studied, as well as 230 samples from patients with geohelminthiases obtained from North Vietnam provinces and 299 samples from Moscow donors. The test sensitivity and specificity were 78.72% and 94.52%, respectively. The dependence of test sensitivity on the intensity of infection has been noted. The calculation of the diagnostic value of enzyme immunoassay makes it possible to use it with respect to the level of the population invaxon: in low level of invaxon (below 32%) D = 2.11M + 0.06, in invaxon level above 32%, D = 1.74M + 0.04. The use of a homologous antigen enhances the test sensitivity.
已研发出一种使用同源和异源抗原的酶免疫测定法用于诊断华支睾吸虫病。研究了251份华支睾吸虫病患者的血清样本，以及230份来自越南北部省份的土源性蠕虫病患者的样本和299份来自莫斯科献血者的样本。该检测的灵敏度和特异性分别为78.72%和94.52%。已注意到检测灵敏度与感染强度的相关性。酶免疫测定法诊断价值的计算使其能够根据人群感染水平使用：在低感染水平（低于32%）时，D = 2.11M + 0.06；在感染水平高于32%时，D = 1.74M + 0.04。使用同源抗原可提高检测灵敏度。
