[怀疑甲氟喹（malarone）有惊厥性副作用]
[Suspected convulsive side-effect of mefloquine (Lariam)].
作者信息
Besser R, Krämer G
机构信息
Neurologische Klinik, Universität Mainz.
出版信息
Nervenarzt. 1991 Dec;62(12):760-1.
PMID:1795756
Abstract
A 20 years old female patient with epileptic seizures (bilateral myoclonus and generalized tonic-clonic seizures (bilateral myoclonus and generalized tonic-clonic seizures) since the age of 13 was treated with valproic acid. Eight hours after 2 of 3 prophylactic antimalarial treatments with mefloquine generalized tonic-clonic seizures occurred. A causal relationship is suggested.
摘要
一名20岁女性患者，自13岁起患有癫痫发作（双侧肌阵挛和全身强直阵挛性发作），一直使用丙戊酸治疗。在用甲氟喹进行3次预防性抗疟治疗中的2次后8小时，出现了全身强直阵挛性发作。提示存在因果关系。
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