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提高美国和墨西哥糖尿病死亡率统计数据的可比性。

Improving the comparability of diabetes mortality statistics in the U.S. and Mexico.

作者信息

Murray Christopher J L, Dias Rodrigo H, Kulkarni Sandeep C, Lozano Rafael, Stevens Gretchen A, Ezzati Majid

机构信息

Harvard School of Public Health, Boston, MA 02115, USA.

出版信息

Diabetes Care. 2008 Mar;31(3):451-8. doi: 10.2337/dc07-1370. Epub 2007 Oct 24.

Abstract

OBJECTIVE

The aim of this study was to increase the cross-state comparability of diabetes mortality statistics related in the U.S. and Mexico.

RESEARCH DESIGN AND METHODS

We used multinomial logistic regression to estimate the effects of individual and community factors on a death for which diabetes was recorded as one of the multiple contributing causes of death (MCD) being assigned to diabetes as the underlying cause of death (UCD) versus assignment to cardiovascular, other noncommunicable, or communicable diseases. We used the model to estimate state-level diabetes death rates that are standardized in the individual and community factors.

RESULTS

Deaths with diabetes as one of the MCD were more likely to be assigned to cardiovascular causes as the UCD if they occurred in hospitals or if an autopsy was performed and if the decedents were from states with higher BMI and systolic blood pressure, were more educated, or had insurance. Adjusting for individual- and community-level factors substantially increased the cross-state correlation of diabetes as the UCD and diabetes as one of the MCD mortality rates. The adjustment also reduced the number of direct diabetes deaths by 10% in the U.S. and by 24% in Mexico. In the U.S., deaths with diabetes as the UCD declined most in Utah, New Mexico, New Jersey, and Louisiana and increased in California and Hawaii. In Mexico, the numbers of adjusted diabetes deaths were smaller than those observed in all states by 3-34%. An additional 126,300 deaths due to ischemic heart disease and stroke in the U.S. and 19,497 in Mexico were attributable to high blood glucose.

CONCLUSIONS

There is a need to improve the comparability of diabetes cause-of-death assignment, especially in relation to cardiovascular diseases.

摘要

目的

本研究的目的是提高美国和墨西哥糖尿病死亡率统计数据的跨州可比性。

研究设计与方法

我们使用多项逻辑回归来估计个体和社区因素对死亡的影响,这些死亡被记录为多种致死原因(MCD)之一,其中糖尿病被指定为根本死因(UCD),而不是被指定为心血管疾病、其他非传染性疾病或传染性疾病。我们使用该模型来估计在个体和社区因素方面标准化的州级糖尿病死亡率。

结果

如果糖尿病作为MCD之一的死亡发生在医院、进行了尸检,且死者来自BMI和收缩压较高、受教育程度较高或有保险的州,那么这些死亡更有可能被指定为心血管疾病作为UCD。对个体和社区层面的因素进行调整后,显著提高了将糖尿病作为UCD和将糖尿病作为MCD死亡率之一的跨州相关性。这种调整还使美国的直接糖尿病死亡人数减少了10%,墨西哥减少了24%。在美国,以糖尿病为UCD的死亡人数在犹他州、新墨西哥州、新泽西州和路易斯安那州下降最多,在加利福尼亚州和夏威夷州有所增加。在墨西哥,调整后的糖尿病死亡人数比所有州观察到的死亡人数少3%-34%。在美国,另有126300例缺血性心脏病和中风死亡以及墨西哥的19497例死亡可归因于高血糖。

结论

有必要提高糖尿病死因判定的可比性,尤其是与心血管疾病相关的可比性。

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